正畸患者局部坏死性溃疡性牙龈炎的非手术牙周治疗和益生菌治疗

Giovanna Mosaico, A. Sinesi, Matteo Fanuli, M. Casalino, Giovanni Mautarelli, C. Casu
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引用次数: 0

摘要

急性坏死性溃疡性牙龈炎是一组侵袭性的半可逆牙周病,通常与深层微生物组改变有关(密螺旋体sp., B. melaninogenicus sp.。中间菌和梭杆菌)和难以去除菌斑。接受固定正畸治疗的患者发生牙周/牙龈疾病的风险较高。治疗弹性和耐药ANUG通常以口袋清创和额外的全身治疗(通常是甲硝唑)为代表。近年来,患者对抗菌药物的耐药性明显增加,益生菌是牙周病非手术治疗的新途径。本工作的目的是报告一例正畸患者难治性ANUG成功治疗局部益生菌罗伊氏乳杆菌。一名患有坏死性溃疡性牙龈炎的16岁女性向我们的私人诊所报告。患者接受局部消毒和牙周清创治疗数月,无好转。我们已经决定将局部益生菌罗伊氏乳杆菌DSM 17938和罗伊氏乳杆菌ATCC PTA 5289与非手术牙周治疗联系起来。将益生菌溶液注射到口袋中,直到溢出,3-5分钟,最后患者不漱口,并建议患者1小时左右不吃不喝。使用局部益生菌治疗牙龈炎和ANUG可以被认为是传统治疗难治性正畸患者的有效替代方法。必须进行进一步的研究,特别是随机临床试验来证实这一初步结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Localized Necrotic Ulceration Gingivitis, in Orthodontic Patient, Treated with Non- Surgical Periodontal Therapy and with Probiotics (L. Reuteri)
Acute Necrotic Ulcerative Gingivitis constitute a group of aggressive semi-reversible periodontal disease usually linked to deep microbiome alterations (Treponema sp., B. melaninogenicus ssp. intermedius and the Fusobacterium sp) and difficult plaque removal. Patients undergoing in fixed orthodontic treatment could have higher risk in periodontal/gum disease development. Therapy for resilient and resistant ANUG is usually represented by pocket debridement and additional systemic therapies (often Metronidazole). In recent years patients resistance to antimicrobial therapies has strongly increased, so probiotic represent a new incoming approach in non surgical periodontal diseases treatment. The aim of this work is to report a case of orthodontic patient with refractory ANUG successfully treated with topical probiotic L. Reuteri. A 16-year-old female with a necrotic ulceration gingivitis reported to our private practice. The patient was submitted to local antiseptics and periodontal debridement for several months without improvement. We had decided to associate a treatment with topical probiotics Lactobacillus reuteri DSM 17938 and lactobacillus reuteri ATCC PTA 5289 to the non-surgical periodontal therapy. The solution of probiotic was injected into the pockets until the spill, for 3-5 minutes and at the end the patient did not rinse the mouth and was advised not to eat and drink for about an hour. The use of topical probiotics in the treatment of gingivitis and ANUG could be considered a valid alternative to conventional treatments for refractory cases in orthodontic patients. Further studies, especially randomized clinical trials, must be performed to confirm this starting result.
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