在科纳克里大学国立医院Ignace Deen进行的8项观察研究

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Touré Ml, Carlos Othon G, Baldé Th, Diallo Sm, Ballo BKJB,, A. Djibo Hamani, F. Sakadi, A. Sakho, DF Kassa, FA Cissé, A. Cissé
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引用次数: 0

摘要

在临床、放射学和热带环境中,神经梅毒背景下发生的脊髓病研究很少。由于脊髓损伤的病因多种多样,脊髓病的梅毒病因诊断的确定性很难确定。患者和方法:我们对2015年1月至2021年12月期间因脊髓疾病住院的269例患者进行了回顾性研究,其中8(8)例患者通过血液和脑脊液中VDRL-TPHA血清学反应阳性和放射学资料诊断为进行性梅毒性脊髓病。所有患者均行磁共振成像检查。结果:神经学症状仅限于感觉-运动脊柱符会学,特别是括约肌疾病,特别是中度泌尿系统疾病,在血液和脑血管液中VDRL-TPHA血清学反应阳性的情况下,没有明显的感染综合征。脊髓。腰椎穿刺显示淋巴细胞增多,平均65%为淋巴细胞为主,高蛋白血症为0.98 ~ 1.36 g/l。所有患者的磁共振成像均显示T2高信号,多个节段或多或少有广泛病变的表达,有助于诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Syphylitical Myelopathies: Study of 8 observations at National Hospital Ignace Deen, University of Conakry
Introduction: Myelopathies occurring in the context of neurosyphilis have been poorly studied clinically, radiologically and in tropical settings. The diagnostic certainty of the syphilitic etiology of myelopathy is difficult to establish because of the multiplicity of causes of spinal cord damage. Patients and Methods: We carried out a retrospective study of 269 patients hospitalized for spinal cord disorders between January 2015 and December 2021, among whom 8 (eight) patients were identified for progressive syphilitic myelopathy diagnosed by the positivity of VDRL-TPHA serological reactions in the blood and cerebrospinal fluid and radiological data. Magnetic resonance imaging was performed in all patients. Results: The neurological signs were limited to the existence of a sensory-motor spinal semiology in particular, paraparesis with sphincter disorders, especially moderate urinary disorders, without an obvious infectious syndrome in a context of positive serological reactions VDRL-TPHA in the blood and cerebrovascular fluid. spinal. Lumbar puncture shows hypercellularity with lymphocyte predominance on average 65% and hyperproteinorachia varying from 0.98 to 1.36 g/l. magnetic resonance imaging performed in all patients contributed to the diagnosis by showing hypersignals in T2, expression of more or less extensive lesions on several segments.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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