参与肌肉萎缩的microRNA和外泌体调控的研究进展

Peitong Wen, Ping Xu, Li Hu, Weibo Zhang, Yuan-yuan Gao
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引用次数: 0

摘要

外泌体是一种特异性的细胞外囊泡。MicroRNA在细胞的交换运输和靶细胞的调控中起着重要的作用。该研究表明,外泌体和内部microRNA作为细胞之间的信使,参与了各种疾病的发展,例如肌肉萎缩。microRNA的调控参与了肌肉萎缩的进程。在临床上,microRNA是肌萎缩的诊断标志物和治疗靶点。本文就参与肌肉萎缩调控的microRNA和外泌体的研究进展作一综述。关键词:MicroRNA;液;肌肉萎缩;监管;研究进展
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advances in the regulation of microRNA and exosomes involved in muscle atrophy
Exosome is a kind of specific extracellular vesicle. MicroRNA plays an important role in the exchanging and transportation of cells and the regulation of target cell. The study shows that exosome and internal microRNA act as messengers between cells, and are involved in development of various diseases, for example muscle atrophy. The microRNA regulation is involved in progress of muscle atrophy. In clinical, microRNA is a diagnostic marker and therapeutic target of muscle atrophy. This review focuses on the research progress of microRNA and exosomes involved in the regulation of muscle atrophy. Key words: MicroRNA; Exosomes; Muscle atrophy; Regulation; Research progress
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