新型冠状病毒肺炎并发急性鼻窦炎2例曲霉与毛霉科菌合并感染

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL

Case Reports in Medicine Pub Date : 2022-03-14 DOI:10.1155/2022/8114388

P. Tabarsi, S. Sharifynia, M. Pourabdollah Toutkaboni, Z. Abtahian, M. Rahdar, A. Mirahmadian, A. Hakamifard

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引用次数: 5

摘要

急性侵袭性真菌性鼻窦炎(AIFR)是一种危及生命的感染，常见于免疫功能低下的患者。在新冠肺炎时代，出现了AIFR的报道，死亡率和发病率都很高。本文报道了两例与COVID-19相关的AIFR，病例1为黄曲霉和arrhizopus，病例2为烟曲霉和arrhizopus。两例患者均接受两性霉素B脂质体治疗，然后泊沙康唑联合积极的坏死组织手术清创，临床效果良好。混合病因可影响预后;因此，需要对这一新的威胁进行进一步的研究。

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Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19

Acute invasive fungal rhinosinusitis (AIFR) is a life-threatening infection often found in immunocompromised patients. In the COVID-19 era, reports of AIFR have emerged, with high mortality and morbidity rate. This paper presents two cases of COVID-19 associated AIFR with the combined proven fungal etiology of Aspergillus flavus and Rhizopus arrhizus in case 1 and Aspergillus fumigatus and Rhizopus arrhizus in case 2. Both patients received liposomal amphotericin B then posaconazole combined with aggressive surgical debridement of necrotic tissues with a favorable clinical outcome. Mixed etiology AIFR can influence the outcome; hence, further studies are required upon this new threat.

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来源期刊

Case Reports in Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

1.70

自引率

0.00%

发文量

审稿时长

13 weeks