Submucosal Elastosis of the Right Colon-A Case Report with Review of the Literature

Submucosal elastosis of the colon is a rarely reported condition that may resemble colonic polyp and amyloid deposition. We report a case of 68-year-old male who underwent screening for colorectal malignant neoplasm. Multiple sessile polyps along with innumerable firm yellow nodules of varying sizes are identified throughout the right colon. Histopathologically, the nodules are characterized by extensive submucosal accumulation of eosinophilic elastic fibers, positive for elastin stain and negative for Congo red stain. The overall findings are consistent with fibroelastoma. The clinical, microscopic, and immunohistochemical characteristics of the current case are reviewed in detail in this report. Other 25 reported cases between 2004-2019 are summarized and their clinical and pathological features are compared with the current case