{"title":"荷叶对大鼠胃溃疡的抗溃疡作用","authors":"G. Vinothapooshan, K. Sundar","doi":"10.1234/JGPT.V3I2.346","DOIUrl":null,"url":null,"abstract":"The effect of Methanolic,chloroform and diethel ether extracts of Adhatoda vasica was investigated in rats to evaluate the anti-ulcer activity by using three models, i.e. Aspirin, Alcohol and pyloric ligation models experimentally induced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, PH, free acidity, total acidity and ulcer index with respect to control.","PeriodicalId":15889,"journal":{"name":"Journal of Global Pharma Technology","volume":"19 1","pages":"7-13"},"PeriodicalIF":0.0000,"publicationDate":"2011-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"13","resultStr":"{\"title\":\"ANTI-ULCER ACTIVITY OF ADHATODA VASICA LEAVES AGAINST GASTRIC ULCER IN RATS\",\"authors\":\"G. Vinothapooshan, K. Sundar\",\"doi\":\"10.1234/JGPT.V3I2.346\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The effect of Methanolic,chloroform and diethel ether extracts of Adhatoda vasica was investigated in rats to evaluate the anti-ulcer activity by using three models, i.e. Aspirin, Alcohol and pyloric ligation models experimentally induced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, PH, free acidity, total acidity and ulcer index with respect to control.\",\"PeriodicalId\":15889,\"journal\":{\"name\":\"Journal of Global Pharma Technology\",\"volume\":\"19 1\",\"pages\":\"7-13\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Global Pharma Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1234/JGPT.V3I2.346\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Global Pharma Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1234/JGPT.V3I2.346","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ANTI-ULCER ACTIVITY OF ADHATODA VASICA LEAVES AGAINST GASTRIC ULCER IN RATS
The effect of Methanolic,chloroform and diethel ether extracts of Adhatoda vasica was investigated in rats to evaluate the anti-ulcer activity by using three models, i.e. Aspirin, Alcohol and pyloric ligation models experimentally induced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, PH, free acidity, total acidity and ulcer index with respect to control.
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