迷走神经切除患者肠道副交感神经支配减少的体内正电子发射断层成像

Neurogastroenterology & Motility Pub Date : 2019-11-12 DOI:10.1111/nmo.13759

T. Fedorova, K. Knudsen, B. Hartmann, J. Holst, F. Viborg Mortensen, K. Krogh, P. Borghammer

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引用次数: 6

摘要

副交感神经病变是许多常见疾病的关键特征，包括糖尿病、神经系统疾病和癌症，但很少有客观的方法来评估副交感神经系统，特别是胃肠道系统的损伤。本研究旨在验证使用11C -多奈哌齐正电子发射断层扫描(PET)来评估迷走神经切除患者的副交感神经完整性。

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In vivo positron emission tomography imaging of decreased parasympathetic innervation in the gut of vagotomized patients

Parasympathetic neuropathy is a key feature in many common disorders, including diabetes, neurological disorders, and cancers, but few objective methods exist for assessing damage to the parasympathetic nervous system, particularly in the gastrointestinal system. This study aimed to validate the use of 11C‐donepezil positron emission tomography (PET) to assess parasympathetic integrity in a group of vagotomized patients.

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Neurogastroenterology & Motility

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