为非整倍体(PGT-A)提供植入前基因检测的实际考虑

Q. Yeung, Ying Xin Zhang, J. Chung, Y. K. Kwok, B. Gui, K. Choy, T. Li
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引用次数: 1

摘要

非整倍体植入前基因检测(PGT-A)在提高生殖成功率、缩短妊娠时间和服务意向治疗方面的应用一直存在争议。然而,许多体外受精(IVF)机构已经因为这样或那样的原因引入了这项服务。鉴于PGT-A不是一项独立的技术,而是一项涉及多个学科的临床服务,本文讨论了影响PGT-A应用成功率的因素,并强调了临床医生、胚胎学和遗传学实验室在提供PGT-A服务时遇到的实际问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Practical Considerations in Providing Preimplantation Genetic Testing for Aneuploidies (PGT-A)
Preimplantation genetic testing for aneuploidies (PGT-A) has been controversial in its application to improve reproductive success, reduce time-to-pregnancy, and serve the intention-to-treat. Nevertheless, many in vitro fertilization (IVF) units have already introduced the service for one reason or another. Given PGT-A is not a stand-alone technique but a clinical service involving several disciplines, this mini review discussed the factors that can influence success rates when PGT-A is applied and highlighted practical issues encountered by clinicians, embryology, and genetics laboratories involved in the provision of PGT-A service.
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