{"title":"系统生物学和合成生物学的认识论方法","authors":"O. Macovei","doi":"10.18662/brain/13.4/400","DOIUrl":null,"url":null,"abstract":"The classical literature in the field of biology approaches the field of life from the perspective of the mechanisms by which the interactions between living systems are managed, while the systemic approach to biology emphasizes the interconnected networks of living nodes and the ways of communication of living systems, which is the very foundation of the idea of live as exchange of information on material or energetic support. More concretely, the emphasis on the informational dimension of biological interactions transfers the research object of synthetic biology from questions regarding the functionality of living systems, to those related to the ways of encoding information inside living structures that allow their configuration and reconfiguration in different evolutionary or constructive – in the case of synthetic biology – contexts. The analysis of the living system as a whole, from a structural-constructive perspective, takes from the systems theory a series of models for understanding the whole as something other than a simple aggregation of the component parts, emphasizing the integrity of the living system in a manner close to the systems approach in the science of complexity.","PeriodicalId":44081,"journal":{"name":"BRAIN-Broad Research in Artificial Intelligence and Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Epistemological Approaches on Systemic and Synthetic Biology\",\"authors\":\"O. Macovei\",\"doi\":\"10.18662/brain/13.4/400\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The classical literature in the field of biology approaches the field of life from the perspective of the mechanisms by which the interactions between living systems are managed, while the systemic approach to biology emphasizes the interconnected networks of living nodes and the ways of communication of living systems, which is the very foundation of the idea of live as exchange of information on material or energetic support. More concretely, the emphasis on the informational dimension of biological interactions transfers the research object of synthetic biology from questions regarding the functionality of living systems, to those related to the ways of encoding information inside living structures that allow their configuration and reconfiguration in different evolutionary or constructive – in the case of synthetic biology – contexts. The analysis of the living system as a whole, from a structural-constructive perspective, takes from the systems theory a series of models for understanding the whole as something other than a simple aggregation of the component parts, emphasizing the integrity of the living system in a manner close to the systems approach in the science of complexity.\",\"PeriodicalId\":44081,\"journal\":{\"name\":\"BRAIN-Broad Research in Artificial Intelligence and Neuroscience\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2022-12-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BRAIN-Broad Research in Artificial Intelligence and Neuroscience\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18662/brain/13.4/400\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BRAIN-Broad Research in Artificial Intelligence and Neuroscience","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18662/brain/13.4/400","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Epistemological Approaches on Systemic and Synthetic Biology
The classical literature in the field of biology approaches the field of life from the perspective of the mechanisms by which the interactions between living systems are managed, while the systemic approach to biology emphasizes the interconnected networks of living nodes and the ways of communication of living systems, which is the very foundation of the idea of live as exchange of information on material or energetic support. More concretely, the emphasis on the informational dimension of biological interactions transfers the research object of synthetic biology from questions regarding the functionality of living systems, to those related to the ways of encoding information inside living structures that allow their configuration and reconfiguration in different evolutionary or constructive – in the case of synthetic biology – contexts. The analysis of the living system as a whole, from a structural-constructive perspective, takes from the systems theory a series of models for understanding the whole as something other than a simple aggregation of the component parts, emphasizing the integrity of the living system in a manner close to the systems approach in the science of complexity.