系统生物学和合成生物学的认识论方法

IF 0.8 Q4 NEUROSCIENCES
O. Macovei
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引用次数: 0

摘要

生物学领域的经典文献从管理生命系统之间相互作用的机制的角度来研究生命领域,而生物学的系统方法强调生命节点的相互联系网络和生命系统的交流方式,这是生命作为物质或能量支持信息交换的理念的基础。更具体地说,强调生物相互作用的信息维度将合成生物学的研究对象从关于生命系统功能的问题转移到与生命结构内部信息编码方式相关的问题,这些信息编码方式允许它们在不同的进化或建设性环境中配置和重新配置——在合成生物学的情况下。从结构建构的角度对生命系统进行整体分析,从系统理论中获取了一系列模型,将整体理解为不同于组成部分的简单集合,以一种接近复杂性科学中的系统方法的方式强调生命系统的完整性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epistemological Approaches on Systemic and Synthetic Biology
The classical literature in the field of biology approaches the field of life from the perspective of the mechanisms by which the interactions between living systems are managed, while the systemic approach to biology emphasizes the interconnected networks of living nodes and the ways of communication of living systems, which is the very foundation of the idea of live as exchange of information on material or energetic support. More concretely, the emphasis on the informational dimension of biological interactions transfers the research object of synthetic biology from questions regarding the functionality of living systems, to those related to the ways of encoding information inside living structures that allow their configuration and reconfiguration in different evolutionary or constructive – in the case of synthetic biology – contexts. The analysis of the living system as a whole, from a structural-constructive perspective, takes from the systems theory a series of models for understanding the whole as something other than a simple aggregation of the component parts, emphasizing the integrity of the living system in a manner close to the systems approach in the science of complexity.
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