Mohsen Herik Dizji, N. Masoudi, Seyfollah Rezaei, Seyedmostafa Seyedmardani, M. Pourjabali
{"title":"结肠癌患者结肠切除术前后骨质疏松发生率及其与血清维生素k2水平的关系","authors":"Mohsen Herik Dizji, N. Masoudi, Seyfollah Rezaei, Seyedmostafa Seyedmardani, M. Pourjabali","doi":"10.52547/umj.33.2.106","DOIUrl":null,"url":null,"abstract":"Background & Aims : Colorectal cancer is one of the most common cancers of the gastrointestinal tract, caused by predisposing factors like lifestyle and aging, and partly, due to genetic and inherited disorders. Due to the increasing incidence of this cancer in Iran, the present study was designed to determine the prevalence of osteoporosis and its relationship with serum levels of vitamin K2 in the patients with colon cancer before and after colectomy. Materials &Methods : In this descriptive-analytical study, 38 patients with colon cancer who underwent colectomy in Imam Khomeini Hospital in Urmia were included in the study. Demographic information, BMD, and vitamin K2 levels of the patients before and after colectomy were collected and recorded in a checklist. Data were analyzed using SPSS Version 17 statistical software. Results : From 38 patients with colorectal cancer, 34.2% were male and 65.8% were female. The mean age of the patients was 58.5 ± 12.7 years. Reviewing bone density examinations done by Dual Energy X-Ray Absorptiometry (DXA) in hip and spine of the patients showed that osteoporosis was higher in both places after colectomy, and their significant differences between them (P-Values were 0.043 for hip and P0.009 for spine). Conclusion : The results of this study showed that osteoporosis in the hip and spine of the patients with colon cancer increased after colectomy compared to it before colectomy. However, the correlation between serum vitamin K2 levels and osteoporosis was not significant.","PeriodicalId":21996,"journal":{"name":"Studies in Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"OSTEOPOROSIS FREQUENCY AND ITS RELATIONSHIP WITH SERUM LEVEL OF VITAMIN K2 IN COLON CANCER PATIENTS BEFORE AND AFTER COLECTOMY\",\"authors\":\"Mohsen Herik Dizji, N. Masoudi, Seyfollah Rezaei, Seyedmostafa Seyedmardani, M. Pourjabali\",\"doi\":\"10.52547/umj.33.2.106\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background & Aims : Colorectal cancer is one of the most common cancers of the gastrointestinal tract, caused by predisposing factors like lifestyle and aging, and partly, due to genetic and inherited disorders. Due to the increasing incidence of this cancer in Iran, the present study was designed to determine the prevalence of osteoporosis and its relationship with serum levels of vitamin K2 in the patients with colon cancer before and after colectomy. Materials &Methods : In this descriptive-analytical study, 38 patients with colon cancer who underwent colectomy in Imam Khomeini Hospital in Urmia were included in the study. Demographic information, BMD, and vitamin K2 levels of the patients before and after colectomy were collected and recorded in a checklist. Data were analyzed using SPSS Version 17 statistical software. Results : From 38 patients with colorectal cancer, 34.2% were male and 65.8% were female. The mean age of the patients was 58.5 ± 12.7 years. Reviewing bone density examinations done by Dual Energy X-Ray Absorptiometry (DXA) in hip and spine of the patients showed that osteoporosis was higher in both places after colectomy, and their significant differences between them (P-Values were 0.043 for hip and P0.009 for spine). Conclusion : The results of this study showed that osteoporosis in the hip and spine of the patients with colon cancer increased after colectomy compared to it before colectomy. However, the correlation between serum vitamin K2 levels and osteoporosis was not significant.\",\"PeriodicalId\":21996,\"journal\":{\"name\":\"Studies in Medical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Studies in Medical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52547/umj.33.2.106\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Studies in Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52547/umj.33.2.106","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景与目的:结直肠癌是最常见的胃肠道癌症之一,其发病因素包括生活方式和年龄等易感因素,部分原因是遗传和遗传疾病。由于这种癌症在伊朗的发病率越来越高,本研究旨在确定结肠切除术前后结肠癌患者骨质疏松症的患病率及其与血清维生素K2水平的关系。材料与方法:在本描述性分析研究中,38例在乌尔米亚伊玛目霍梅尼医院行结肠切除术的结肠癌患者被纳入研究。收集患者结肠切除术前后的人口统计信息、骨密度和维生素K2水平,并记录在检查表中。数据分析采用SPSS Version 17统计软件。结果:38例结直肠癌患者中,男性占34.2%,女性占65.8%。患者平均年龄58.5±12.7岁。回顾患者髋部和脊柱双能x线骨密度检查(DXA)显示,结肠切除术后髋部和脊柱骨质疏松程度均较高,且两者之间存在显著性差异(髋部p值为0.043,脊柱p值为P0.009)。结论:本研究结果显示结肠切除术后结肠癌患者髋部和脊柱骨质疏松症较结肠切除术前加重。然而,血清维生素K2水平与骨质疏松症之间的相关性不显著。
OSTEOPOROSIS FREQUENCY AND ITS RELATIONSHIP WITH SERUM LEVEL OF VITAMIN K2 IN COLON CANCER PATIENTS BEFORE AND AFTER COLECTOMY
Background & Aims : Colorectal cancer is one of the most common cancers of the gastrointestinal tract, caused by predisposing factors like lifestyle and aging, and partly, due to genetic and inherited disorders. Due to the increasing incidence of this cancer in Iran, the present study was designed to determine the prevalence of osteoporosis and its relationship with serum levels of vitamin K2 in the patients with colon cancer before and after colectomy. Materials &Methods : In this descriptive-analytical study, 38 patients with colon cancer who underwent colectomy in Imam Khomeini Hospital in Urmia were included in the study. Demographic information, BMD, and vitamin K2 levels of the patients before and after colectomy were collected and recorded in a checklist. Data were analyzed using SPSS Version 17 statistical software. Results : From 38 patients with colorectal cancer, 34.2% were male and 65.8% were female. The mean age of the patients was 58.5 ± 12.7 years. Reviewing bone density examinations done by Dual Energy X-Ray Absorptiometry (DXA) in hip and spine of the patients showed that osteoporosis was higher in both places after colectomy, and their significant differences between them (P-Values were 0.043 for hip and P0.009 for spine). Conclusion : The results of this study showed that osteoporosis in the hip and spine of the patients with colon cancer increased after colectomy compared to it before colectomy. However, the correlation between serum vitamin K2 levels and osteoporosis was not significant.