糖尿病患者颈动脉病变

Prilozi Pub Date : 2014-12-01 DOI:10.1515/prilozi-2015-0019
M. Bosevski
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引用次数: 5

摘要

关于颈动脉疾病与糖尿病的相互作用有两种观点:糖尿病已被认为是无症状和有症状的颈动脉疾病存在和发展的主要决定因素之一;颈动脉内膜-中膜厚度被定义为对这一人群进行风险分层的有用工具。高血糖、糖尿病持续时间、动脉高血压、胆固醇和炎症标志物已经被确定为糖尿病患者颈动脉粥样硬化的独立因素,而根据我们自己的研究结果,衰老是该人群颈动脉粥样硬化的预测因子。本文重点介绍糖尿病患者(特别是2型糖尿病)危险因素的特殊性,以及这些患者合并卒中和/或颈动脉疾病的管理和降低风险的循证指南。目前有脑血管症状的糖尿病患者推荐颈动脉超声检查。由于糖尿病的患病率不断增加,我们试图解决在糖尿病人群颈动脉疾病的筛查标准的更新。建议至少有一种以上危险因素的糖尿病患者和60岁以上的糖尿病患者服用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Carotid Artery Disease in Diabetic Patients
Abstract There are two points of view on the interplay between carotid artery disease and diabetes mellitus: Diabetes mellitus has been recognized as one of the main determinants for the presence and progression of asymptomatic and symptomatic carotid artery disease; and carotid intima-media thickness has been defined as a useful tool for risk stratification of this population. Hyperglycaemia, duration of diabetes, arterial hypertension, cholesterol and inflammatory markers have previously been determined as independent factors for carotid atherosclerosis in diabetes, and aging as its predictor in this population by our own results. This paper focuses on the particularities of risk factors in diabetic patients (especially in type 2) and evidence-based guidelines for the management and risk reduction of these patients with stroke and/or carotid artery disease. At present, carotid ultrasound is recommended in diabetic patients with cerebrovascular symptoms. Since the prevalence of diabetes increases constantly, we attempt to address refreshment of criteria for screening of carotid artery disease in the diabetic population. It could be recommended for diabetic patients with at least one more risk factors and for diabetic patients above 60 years of age.
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