9,10-蒽醌-2-磺酸钠与DNA相互作用的光谱研究

Wen-You Li , Zu-Hong Lu , Jin-Gou Xu , Xiang-Qun Guo , Qing-Zhi Zhu
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引用次数: 2

摘要

9,10-蒽醌-2-磺酸钠(AQS)结合双螺旋DNA具有高亲和力,从吸收和荧光光谱数据推断。吸收光谱、KI猝灭研究、竞争结合研究和热变性实验结果表明AQS与DNA碱基的插入结合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spectroscopic study on the interaction between sodium 9,10-anthraquinone-2-sulfonate and DNA

Sodium 9,10-anthraquinone-2-sulfonate (AQS) binds to the double helical DNA with a high affinity, as deduced from the absorption and fluorescence spectral data. The results of absorption spectra, KI quenching studies, competitive binding studies, and thermal denaturation experiments suggested the intercalative binding of AQS into DNA bases.

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