可能与伟哥有关的视觉副作用

Journal of Toxicology-cutaneous and Ocular Toxicology Pub Date : 2000-01-01 DOI:10.3109/15569520009051474

F. T. Fraunfelder, A. Laties

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引用次数: 5

摘要

枸橼酸西地那非(伟哥)是一种治疗勃起功能障碍的口服药物，是PDE-5的选择性抑制剂，也是PDE-6的选择性抑制剂，存在于视网膜中。该药有一些罕见的、剂量依赖性的、可逆的眼部副作用。报告的眼部副作用包括颜色感知改变、视力模糊、光感知改变、视网膜电图改变和结膜充血。

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Visual Side Effects Possibly Associated with Viagra

Abstract Sildenafil citrate (Viagra), an oral therapy for erectile dysfunction, is a selective inhibitor of PDE-5, but also PDE-6, which is found in the retina. This drug has some ocular side effects which are uncommon, dose-dependent, and reversible. Reported ocular side effects include changes in color perception, blurred vision, changes in light perception, electoretinogram changes, and conjunctival hyperemia.

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Journal of Toxicology-cutaneous and Ocular Toxicology

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