Dong Wook Kim, Tae-Seon Baek, Yun-Jeong Kim, Sung-Kyu Choi, D. Lee
{"title":"水母胶原蛋白提取物的保湿效果","authors":"Dong Wook Kim, Tae-Seon Baek, Yun-Jeong Kim, Sung-Kyu Choi, D. Lee","doi":"10.15230/SCSK.2016.42.2.153","DOIUrl":null,"url":null,"abstract":"In this study, we investigated the moisturizing effects of collagen extract from jellyfish. The mositurizing effects were measured by the caspase 14 expression, filaggrin, hyaluronan synthase-3 (HAS-3), aquaporin-3 (AQP-3) and desmocollin (DSC). As a results, effect of caspase 14 mRNA expression of collagen extract are similar to that of retinoic acid (RA) which is a reference control. And the collagen extract showed inhibitory of filaggrin, HAS-3, AQP-3 and DSC mRNA expression of 211.7%, 139.9%, 212.5% and 116.8% respectively, at the concentration of 2%. Therefore, our study suggested that jellyfish collagen extract has considerable potential as a cosmetics ingredient with moisturizing effect.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"3 1","pages":"153-162"},"PeriodicalIF":0.0000,"publicationDate":"2016-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"8","resultStr":"{\"title\":\"Moisturizing Effect of Jellyfish Collagen Extract\",\"authors\":\"Dong Wook Kim, Tae-Seon Baek, Yun-Jeong Kim, Sung-Kyu Choi, D. Lee\",\"doi\":\"10.15230/SCSK.2016.42.2.153\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this study, we investigated the moisturizing effects of collagen extract from jellyfish. The mositurizing effects were measured by the caspase 14 expression, filaggrin, hyaluronan synthase-3 (HAS-3), aquaporin-3 (AQP-3) and desmocollin (DSC). As a results, effect of caspase 14 mRNA expression of collagen extract are similar to that of retinoic acid (RA) which is a reference control. And the collagen extract showed inhibitory of filaggrin, HAS-3, AQP-3 and DSC mRNA expression of 211.7%, 139.9%, 212.5% and 116.8% respectively, at the concentration of 2%. Therefore, our study suggested that jellyfish collagen extract has considerable potential as a cosmetics ingredient with moisturizing effect.\",\"PeriodicalId\":17401,\"journal\":{\"name\":\"Journal of the Society of Cosmetic Scientists of Korea\",\"volume\":\"3 1\",\"pages\":\"153-162\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Society of Cosmetic Scientists of Korea\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15230/SCSK.2016.42.2.153\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Society of Cosmetic Scientists of Korea","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15230/SCSK.2016.42.2.153","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
In this study, we investigated the moisturizing effects of collagen extract from jellyfish. The mositurizing effects were measured by the caspase 14 expression, filaggrin, hyaluronan synthase-3 (HAS-3), aquaporin-3 (AQP-3) and desmocollin (DSC). As a results, effect of caspase 14 mRNA expression of collagen extract are similar to that of retinoic acid (RA) which is a reference control. And the collagen extract showed inhibitory of filaggrin, HAS-3, AQP-3 and DSC mRNA expression of 211.7%, 139.9%, 212.5% and 116.8% respectively, at the concentration of 2%. Therefore, our study suggested that jellyfish collagen extract has considerable potential as a cosmetics ingredient with moisturizing effect.
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