GtoPdb v.2023.1中的Kisspeptin受体

A. Davenport, J. Maguire, E. J. Mead, Adam J. Pawson
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引用次数: 0

摘要

kisspeptin受体(由NC-IUPHAR kisspeptin受体小组委员会商定的命名法[11]),与神经肽FF (NPFF)、催乳素释放肽(PrP)和QRFP受体(临时命名法)一样,对具有精氨酸-苯丙氨酸-酰胺(RFamide)基序的内源性肽作出反应。kisspeptin-54 (KP54,原称为metastin)、kisspeptin-13 (KP13)和kisspeptin-10 (KP10)是从KISS1 (Q15726)基因产物中切割出来的具有生物活性的肽。kisspeptin在癌症转移、生育/青春期调节和葡萄糖稳态等方面发挥作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Kisspeptin receptor in GtoPdb v.2023.1
The kisspeptin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the kisspeptin receptor [11]), like neuropeptide FF (NPFF), prolactin-releasing peptide (PrP) and QRFP receptors (provisional nomenclature) responds to endogenous peptides with an arginine-phenylalanine-amide (RFamide) motif. kisspeptin-54 (KP54, originally named metastin), kisspeptin-13 (KP13) and kisspeptin-10 (KP10) are biologically-active peptides cleaved from the KISS1 (Q15726) gene product. Kisspeptins have roles in, for example, cancer metastasis, fertility/puberty regulation and glucose homeostasis.
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