分子信号通路与胃癌癌痛的关系

国际肿瘤学杂志 Pub Date : 2019-12-08 DOI:10.3760/CMA.J.ISSN.1673-422X.2019.12.010

Ziyang Xing, Chunxia Sun

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引用次数: 1

摘要

胃癌中丝裂原活化的蛋白激酶、磷酸肌醇3-激酶/蛋白激酶B、amp活化的蛋白激酶、环加氧酶2/核因子-κB、Wnt/β-catenin等分子信号通路与癌痛的发生发展密切相关。了解胃癌分子信号通路在癌痛中的表达及其作用，有望为癌痛的治疗提供新的思路。关键词:胃肿瘤;癌症疼痛;信号通路

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Molecular signaling pathways and cancer pain in gastric cancer

The molecular signaling pathways in gastric cancer, such as mitogen-activated protein kinase, phosphoinoinositide 3-kinase/protein kinase B, AMP-activated protein kinase, cyclooxygenase 2/nuclear factor-κB and Wnt/β-catenin pathways are closely related to the occurrence and development of cancer pain. To understand the expression and role of gastric cancer molecular signaling pathway in cancer pain is expected to provide a new idea for the treatment of cancer pain. Key words: Stomach neoplasms; Cancer pain; Signaling pathway

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国际肿瘤学杂志

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12123

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