{"title":"在模拟逆流色谱生物反应器-分离器中结合生物反应和分离用于乳糖水解","authors":"M. T. Shieh, P. E. Barker","doi":"10.1002/(SICI)1097-4660(199607)66:3<265::AID-JCTB503>3.0.CO;2-#","DOIUrl":null,"url":null,"abstract":"The hydrolysis of lactose using the enzyme lactase from Aspergillus oryzae and the simultaneous separation of the products galactose and glucose was examined in a Simulated Counter-Current Chromatographic Bioreactor-Separator (SCCR-S) system. The system was operated in continuous and batch modes and the results obtained used to compare the performance in both modes. Mathematical modelling and computer simulation of the system operating in the continuous mode are reported.","PeriodicalId":15303,"journal":{"name":"Journal of Chemical Technology & Biotechnology","volume":"39 1","pages":"265-278"},"PeriodicalIF":0.0000,"publicationDate":"1996-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"37","resultStr":"{\"title\":\"Combined bioreaction and separation in a simulated counter-current chromatographic bioreactor-separator for the hydrolysis of lactose\",\"authors\":\"M. T. Shieh, P. E. Barker\",\"doi\":\"10.1002/(SICI)1097-4660(199607)66:3<265::AID-JCTB503>3.0.CO;2-#\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The hydrolysis of lactose using the enzyme lactase from Aspergillus oryzae and the simultaneous separation of the products galactose and glucose was examined in a Simulated Counter-Current Chromatographic Bioreactor-Separator (SCCR-S) system. The system was operated in continuous and batch modes and the results obtained used to compare the performance in both modes. Mathematical modelling and computer simulation of the system operating in the continuous mode are reported.\",\"PeriodicalId\":15303,\"journal\":{\"name\":\"Journal of Chemical Technology & Biotechnology\",\"volume\":\"39 1\",\"pages\":\"265-278\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"37\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Chemical Technology & Biotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/(SICI)1097-4660(199607)66:3<265::AID-JCTB503>3.0.CO;2-#\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chemical Technology & Biotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/(SICI)1097-4660(199607)66:3<265::AID-JCTB503>3.0.CO;2-#","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Combined bioreaction and separation in a simulated counter-current chromatographic bioreactor-separator for the hydrolysis of lactose
The hydrolysis of lactose using the enzyme lactase from Aspergillus oryzae and the simultaneous separation of the products galactose and glucose was examined in a Simulated Counter-Current Chromatographic Bioreactor-Separator (SCCR-S) system. The system was operated in continuous and batch modes and the results obtained used to compare the performance in both modes. Mathematical modelling and computer simulation of the system operating in the continuous mode are reported.