富白细胞血小板血浆对家兔正畸牙齿加速运动的影响

IF 1.9 3区 医学 Q1 Dentistry
Theerasak Nakornnoi, C. Leethanakul, B. Samruajbenjakun
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引用次数: 12

摘要

目的观察局部注射富白细胞血小板血浆(L-PRP)对家兔正畸牙运动的影响。方法23只雄性新西兰大白兔采用开口设计。在上颌第一前磨牙上用100 g镍钛闭合线圈弹簧移动牙齿。L-PRP随机在上颌一侧第一前磨牙颊部和舌部粘膜下注射,另一侧作为对照,接受生理盐水。在第0天、第3天、第7天、第14天、第21天和第28天通过三维数字模型评估牙齿的移动量。在第0天、第7天、第14天和第28天分别检测组织学结果和破骨细胞数量。结果L-PRP组在各观察时段的累计牙移量均显著增加。然而,仅在第0-7天和第7-14天观察到牙齿移动率明显较高。第7、14天,L-PRP组破骨细胞数量显著增加。结论局部注射L-PRP可使牙齿移动速度短暂增加,破骨细胞数量增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The influence of leukocyte-platelet-rich plasma on accelerated orthodontic tooth movement in rabbits
Objective To determine the effects of a local injection of leukocyte-platelet-rich plasma (L-PRP) on orthodontic tooth movement in rabbits. Methods Twenty-three male New Zealand white rabbits were included in a split-mouth design. Tooth movement with a 100-g nickel-titanium closed-coil spring was performed on the maxillary first premolars. L-PRP was injected submucosally at the buccal and lingual areas of the first premolar in one random side of the maxilla and the other side served as the control and received normal saline. The amount of tooth movement was assessed on three-dimensional digital models on days 0, 3, 7, 14, 21, and 28. Histological findings and osteoclast numbers were examined on day 0 as the baseline and on days 7, 14, and 28. Results The L-PRP group showed significantly greater cumulative tooth movement at all observed periods. However, a significantly higher rate of tooth movement was observed only on days 0–7 and 7–14. The osteoclast numbers were significantly increased in the L-PRP group on days 7 and 14. Conclusions Local injection of L-PRP resulted in a transient increase in the rate of tooth movement and higher osteoclast numbers.
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来源期刊
Korean Journal of Orthodontics
Korean Journal of Orthodontics Dentistry-Orthodontics
CiteScore
2.60
自引率
10.50%
发文量
48
审稿时长
3 months
期刊介绍: The Korean Journal of Orthodontics (KJO) is an international, open access, peer reviewed journal published in January, March, May, July, September, and November each year. It was first launched in 1970 and, as the official scientific publication of Korean Association of Orthodontists, KJO aims to publish high quality clinical and scientific original research papers in all areas related to orthodontics and dentofacial orthopedics. Specifically, its interest focuses on evidence-based investigations of contemporary diagnostic procedures and treatment techniques, expanding to significant clinical reports of diverse treatment approaches. The scope of KJO covers all areas of orthodontics and dentofacial orthopedics including successful diagnostic procedures and treatment planning, growth and development of the face and its clinical implications, appliance designs, biomechanics, TMJ disorders and adult treatment. Specifically, its latest interest focuses on skeletal anchorage devices, orthodontic appliance and biomaterials, 3 dimensional imaging techniques utilized for dentofacial diagnosis and treatment planning, and orthognathic surgery to correct skeletal disharmony in association of orthodontic treatment.
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