坏死性筋膜炎54例临床分析。

C. Tsai, S. D. Lin, C. Lai, C. Chou
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引用次数: 15

摘要

坏死性筋膜炎是一种严重的,有时危及生命的软组织感染,其特征是筋膜和皮下组织迅速广泛坏死。本文回顾了五十四例坏死性筋膜炎病例。其中糖尿病患者25例(46%)。大多数伤口细菌培养(71%)产生混合生长。6例患者培养阴性,14例患者单菌生长(29%)。主要生长的微生物是链球菌、葡萄球菌和大肠杆菌。总死亡率为22%(12/54)。这些患者死于全身脓毒症并发症。所有12例死亡均因延迟清创所致(平均在出现初始症状后25天)。我们的研究表明,对所有坏死组织的早期识别和及时清创对于降低这种潜在致命疾病的死亡率至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A clinical analysis of necrotizing fasciitis: a review of 54 cases.
Necrotizing fasciitis is a severe and sometimes life-threatening soft tissue infection that is characterized by rapidly widespreading necrosis of fascia and subcutaneous tissue. Fifty-four cases of necrotizing fasciitis were reviewed over a 5-year period. Among them, 25 patients (46%) had diabetes mellitus. The majority of the wound bacterial cultures (71%) yielded a mixed growing. There were negative cultures in six patients, and single organism growth in 14 patients (29%). The predominant organisms growth were Streptococci, Staphylococci, and Escherichia coli. The overall mortality rate was 22% (12/54). Death was caused by systemic septic complications in these patients. All 12 mortalities resulted from delayed debridement (averaging 25 days after initial symptoms appeared). Our study indicates that the early recognition and prompt debridement of all necrotic tissue is essential for reducing the mortality rates of this potentially lethal condition.
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