{"title":"硫代三唑啉对社区获得性肺炎患者细胞和体液免疫状态的影响","authors":"V. I. Vishnevskij, I. I. Mironenko, O. Demyanenko","doi":"10.18413/2075-4728-2018-41-4-558-567","DOIUrl":null,"url":null,"abstract":"149 patients with community-acquired pneumonia, the influence of the antioxidant tiotriazoline on the state of cellular and humoral immunity was studied. Studies have shown that out-of-hospital pneumonia occurs against the background of secondary immunodeficiency, which is manifested by a decrease in the total circulating T-lymphocytes and their subpopulations: NK-cells, T-helper cells, T-suppressors, Ig A and Ig G increase in Ig M decrease. Tiotriazoline in the complex therapy of patients with community-acquired pneumonia is accompanied by a decrease in both total T-lymphocytopenia and their subpopulations against the background of an increase in the content of immunoglobulins of class Ig M reduction in immunoglobulin classes Ig A and Ig G. of changes in cellular and humoral immunity in patients with community-acquired against the background of course treatment with thiotriazoline","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"77 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effect of thiotriazoline on the state of cellular and humoral immunity in patients with community-acquired pneumonia\",\"authors\":\"V. I. Vishnevskij, I. I. Mironenko, O. Demyanenko\",\"doi\":\"10.18413/2075-4728-2018-41-4-558-567\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"149 patients with community-acquired pneumonia, the influence of the antioxidant tiotriazoline on the state of cellular and humoral immunity was studied. Studies have shown that out-of-hospital pneumonia occurs against the background of secondary immunodeficiency, which is manifested by a decrease in the total circulating T-lymphocytes and their subpopulations: NK-cells, T-helper cells, T-suppressors, Ig A and Ig G increase in Ig M decrease. Tiotriazoline in the complex therapy of patients with community-acquired pneumonia is accompanied by a decrease in both total T-lymphocytopenia and their subpopulations against the background of an increase in the content of immunoglobulins of class Ig M reduction in immunoglobulin classes Ig A and Ig G. of changes in cellular and humoral immunity in patients with community-acquired against the background of course treatment with thiotriazoline\",\"PeriodicalId\":8785,\"journal\":{\"name\":\"Belgorod State University Scientific bulletin Medicine Pharmacy\",\"volume\":\"77 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Belgorod State University Scientific bulletin Medicine Pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18413/2075-4728-2018-41-4-558-567\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Belgorod State University Scientific bulletin Medicine Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18413/2075-4728-2018-41-4-558-567","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The effect of thiotriazoline on the state of cellular and humoral immunity in patients with community-acquired pneumonia
149 patients with community-acquired pneumonia, the influence of the antioxidant tiotriazoline on the state of cellular and humoral immunity was studied. Studies have shown that out-of-hospital pneumonia occurs against the background of secondary immunodeficiency, which is manifested by a decrease in the total circulating T-lymphocytes and their subpopulations: NK-cells, T-helper cells, T-suppressors, Ig A and Ig G increase in Ig M decrease. Tiotriazoline in the complex therapy of patients with community-acquired pneumonia is accompanied by a decrease in both total T-lymphocytopenia and their subpopulations against the background of an increase in the content of immunoglobulins of class Ig M reduction in immunoglobulin classes Ig A and Ig G. of changes in cellular and humoral immunity in patients with community-acquired against the background of course treatment with thiotriazoline
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