内皮素和前列腺癌

Zhang Jun-qiao
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摘要

内皮素是最强的血管收缩剂,具有广泛的生物学功能。内皮素对前列腺癌细胞具有促有丝分裂和抗凋亡的作用。同时还发现内皮素能诱导癌组织血管生成。此外,内皮素已被证实参与肿瘤转移和癌痛。提示内皮素在前列腺癌的发生、发展过程中起重要作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endothelin and prostate cancer
Endothelin is the strongest vasoconstrictor and has extensive biological functions.Recently Endothelin has been re- ported to be mitogenic and anti-apoptotic for prostate cancer cell.And it is also found that but endothelin can induce angiopoiesis in the cancer tissue.Additionally,endothelin has been confirmed to be involved in cancer metastasis and cancer pain.These all suggest that en- dothelin plays an important role in the onset and process of the prostate cancer.
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