Nitesh D. Punyapreddiwar, A. Wankhade, S. Zodape, Umesh R. Pratap
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Saccharomyces cerevisiae Catalyzed Cyclocondensation Reaction: Synthesis of Pyrazoline
A simple, efficient, and environment friendly method has been developed for the synthesis of pyrazoline by the cyclocondensation of chalcones and hydrazine hydrate using very cheaper catalyst, baker’s yeast (Saccharomyces cerevisiae). The 3,5-diphenyl pyrazolines are synthesized in moderate to good yield. The method also overcomes drawbacks of the previous pyrazoline synthetic methods and provides a new efficient route to 3,5-diphenyl pyrazoline derivatives.
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