苏丹孕妇血红蛋白和红细胞计数

Manal Hamed Awad Elmadih, A. Khalid, Ibrahim Abdelrhim Ali, Adam Hussein, Omer Abd elaziz Musa
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摘要

本研究探讨了苏丹孕妇妊娠的生理变化,旨在评估妊娠对苏丹孕妇红细胞、堆积细胞体积(PCV)和血红蛋白的影响,并将PCV作为苏丹妇女在使用或不使用铁和叶酸补充剂的不同孕期血液稀释的指标进行关联。研究人员采用了横断面研究,该研究适用于2019年至2020年在苏丹港产科医院接受产前护理的300名孕妇。使用化学清洁和无菌的一次性针头采集样本,所有血液样本均使用注射器和拭子,每位参与者取4.5 mL血液放入含有抗凝剂乙二胺四乙酸(EDTA)的试管中,轻轻混合5至6次,使用血液分析仪(Sysmex XP 300)进行全血计数。研究发现,90名孕妇在妊娠第一、第二、第三三个孕期的血红蛋白(Hb)均值分别为11.3±1.4 g/dl、11.4±1.4 g/dl和10.3±1.2 g/dl。研究还发现PCV的平均值为33.35%。此外,与妊娠早期(血液稀释)相比,妊娠晚期Hb较低。苏丹未怀孕女性贫血的临界值甚至可以低于11g/dl,因为发现正常水平低于国际标准。如果Hb低于9g/dl,则考虑妊娠期血液稀释性贫血。该研究建议在怀孕期间修改贫血的诊断,因为该研究表明Hb水平低于9g/dl(66%)可以作为临界值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hemoglobin and Red Blood Cells Count in Pregnant Sudanese Women
The study discussed the physiological changes of pregnancy in Sudanese pregnant women the study aimed to assess the effect of pregnancy in Red blood cell, Packed Cell Volume (PCV) and hemoglobin among Sudanese pregnant women, and to correlate the PCV as an indicator of hemodilution in different trimesters among Sudanese women using or not using iron and folic acid supplement. The researcher used across sectional study which applied on 300 pregnant women presented to Port-Sudan obstetrical Hospital for antenatal care from 2019 to 2020. The samples were collected with Chemically clean and sterile disposable needles, syringes and swab were used for all blood samples, 4.5 mL of blood was collected from each participant into a tube containing the anticoagulant Ethylene Diamine Tetraacetic Acid (EDTA), gently mixed the tube five to six times A full blood count was performed using Hematological analyzer (Sysmex XP 300). The study found out that 90 women in each trimester of pregnancy (first, second and third) the mean value of Hemoglobin (Hb) in pregnant women was 11.3±1.4 g/dl, 11.4 ±1.4 g/dl and 10.3±1.2 g/dl in 1st, 2nd and 3rd trimester respectively. The study also found out that the mean value of PCV was 33.35%. Moreover, Hb was lower during 3rd trimester compared with 1st (hemodilution). The cut off level for anemia in Sudanese non pregnant females could be even lower than 11g/dl as the normal level was found to be lower than the international one. Due to hemodilution anemia in pregnancy is considered if Hb less than 9g/dl. The study recommends that diagnosis of anemia should be revised during pregnancy as this study has shown Hb level less than 9g/dl (66%) can be the cut off level.
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