从Tricuspidata果实果皮中提取新的细胞毒性葫芦素

Natural Product Letters Pub Date : 2002-01-01 DOI:10.1080/1057563029001/4755

L. P. Mai, D. Guénard, M. Fránck, M. Van Tri, C. Gaspard, T. Sévenet

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引用次数: 18

摘要

在越南北部收集的tricuspidata果实提取物被发现对KB细胞有细胞毒性。用生物测定法分离了一系列葫芦素，其中两种是新发现的:三葡萄糖苷和2- o -糖葫芦素j。

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New Cytotoxic Cucurbitacins from the Pericarps of Trichosanthes Tricuspidata Fruits

An extract of the fruits of Trichosanthes tricuspidata collected in North Vietnam was found cytotoxic in KB cells. A bioassay-guided fractionation led to the isolation of a series of cucurbitacins of which two are new:tricuspidatin and 2-O-glucocucurbitacin J. Their isolation and structure determination are described.

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Natural Product Letters

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