伊拉克山羊生长分化因子9 (GDF9)基因遗传方差分析及其与精液质量的关系

Amal Hamdi Jassim, S. H. Al-Azzawi
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引用次数: 1

摘要

生长分化因子9 (Growth differentiation factor 9, GDF9)是TGFß超家族成员,在女性卵巢卵泡发育和排卵率中起关键作用。然而,它在山羊睾丸中的作用尚未阐明。因此,本研究探讨了GDF9突变对雄鹿新鲜精液质量的影响。利用直接测序技术筛选山羊GDF9外显子1中可能存在的SNP位点,在当地15只伊拉克雄鹿中鉴定出1个阳性位点2006 CTC < CTA (leu < leu)。方差分析表明,在All中,繁殖值对浓度、个体运动和顶体完整性有显著影响,对显性效应对体积、个体运动和顶体完整性有显著影响。所有性状的遗传变异都很低,这意味着环境变化很大。这项研究首次显示了GDF9在雄性山羊精子发生的开始或维持中的重要关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Estimation of Genetic Variance Based on the Growth Differentiation Factor 9 (GDF9) Gene and its Association with Semen quality in Local Iraqi Goats
Growth differentiation factor 9 (GDF9) is a member of the TGFß superfamily that plays a critical role in females' ovarian follicular development and ovulation rate. However, its role in the testis has not been elucidated in Goats. Therefore, this study investigated the effects of GDF9 mutations on the quality of fresh semen in Bucks. Direct sequencing was used to screen possible SNP loci in the goat GDF9 exon one, one SNP locus site 2006 CTC < CTA ( leu < leu ) was identified positively in 15 local Iraqi Bucks. Analysis of variance revealed that significant effect of breeding value for concentration, individual ( p > 0.05) movement, and Acrosome integrity, in All, so of dominance effects of volume, Individual movement, and Acrosome integrity. All traits have low genetic variation, which means that the environment varies high. This study is the first to show a significant association of GDF9 in the initiation or maintenance of spermatogenesis in male goats.
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