{"title":"高效液相色谱法测定中国石竹提取物中4-羟基-3-甲氧基肉桂醇含量的验证","authors":"Jing Ji, Jie Cao, Jianming Cheng","doi":"10.5539/IJB.V12N3P40","DOIUrl":null,"url":null,"abstract":"Stachyuri medulla helwingiae medulla is a wild used genus in clinic, especially in promoting lactation. Most study confirmed it’s evidently rich in polysaccharide. In this study, a HPLC method for the quantification of Coniferyl alcohol (4-Hydroxy-3-methoxycinnamyl alcohol) was validated. The results showed that the HPLC method was linear (0.01-0.16mg/ml) with good accuracy, precision and robustness. The content of Coniferyl alcohol in different formula granule ranged from 0.091-0.163mg/g. Thus, the method might be used for the standardization of the extracts based on the Coniferyl alcohol marker.","PeriodicalId":13849,"journal":{"name":"International Journal of Biology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Validation of a HPLC Method for the Determination of 4-Hydroxy-3-methoxycinnamyl Alcohol in Extracts Obtained from Stachyurus Chinensis Franeh\",\"authors\":\"Jing Ji, Jie Cao, Jianming Cheng\",\"doi\":\"10.5539/IJB.V12N3P40\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Stachyuri medulla helwingiae medulla is a wild used genus in clinic, especially in promoting lactation. Most study confirmed it’s evidently rich in polysaccharide. In this study, a HPLC method for the quantification of Coniferyl alcohol (4-Hydroxy-3-methoxycinnamyl alcohol) was validated. The results showed that the HPLC method was linear (0.01-0.16mg/ml) with good accuracy, precision and robustness. The content of Coniferyl alcohol in different formula granule ranged from 0.091-0.163mg/g. Thus, the method might be used for the standardization of the extracts based on the Coniferyl alcohol marker.\",\"PeriodicalId\":13849,\"journal\":{\"name\":\"International Journal of Biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5539/IJB.V12N3P40\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5539/IJB.V12N3P40","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Validation of a HPLC Method for the Determination of 4-Hydroxy-3-methoxycinnamyl Alcohol in Extracts Obtained from Stachyurus Chinensis Franeh
Stachyuri medulla helwingiae medulla is a wild used genus in clinic, especially in promoting lactation. Most study confirmed it’s evidently rich in polysaccharide. In this study, a HPLC method for the quantification of Coniferyl alcohol (4-Hydroxy-3-methoxycinnamyl alcohol) was validated. The results showed that the HPLC method was linear (0.01-0.16mg/ml) with good accuracy, precision and robustness. The content of Coniferyl alcohol in different formula granule ranged from 0.091-0.163mg/g. Thus, the method might be used for the standardization of the extracts based on the Coniferyl alcohol marker.
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