马尾松氯仿提取物体外抗氧化和抗炎活性的研究

科技视界 Pub Date : 2019-09-30 DOI:10.33493/scivis.19.03.04

K. Thanzami, B. Kakoti, C. Lalremruati

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引用次数: 0

摘要

本研究旨在通过体外模型研究马尾松氯仿提取物的抗氧化和抗炎活性。通过2,2 -二苯基-1-苦味酰肼(DPPH)自由基清除活性、还原能力和脂质过氧化测定测定其抗氧化活性。测定了提取物的酚类和类黄酮含量。不同浓度提取液对DPPH和脂质过氧化的抑制率均显著高于标准浓度，还原能力强。提取物中酚类物质和类黄酮含量也显著较高。通过抑制白蛋白变性和人红细胞(HRBC)膜稳定法研究其抗炎活性。与标准对照，不同浓度提取物对白蛋白变性的抑制率和溶血的抑制率均有显著性差异。由此可见，氯仿提取物具有明显的抗炎和抗氧化活性。

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In vitro antioxidant and anti-inflammatory activities of the chloroform extract of Combretum punctatum var squamosum

The objective of this study was to investigate the antioxidant and anti-inflammatory activities of the chloroform extract of Combretum punctatum var squamosum by in vitro models. Antioxidant activity was determined by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, reducing power and lipid peroxidation assays. The phenolic and flavonoid contents of the extract were also assessed. The extract at different concentrations showed significant percent inhibition of DPPH and lipid peroxidation and high reducing power when compared with the standard. The extract also showed a significantly high content of phenolics and flavonoids. Anti-inflammatory activity was studied by inhibition of albumin denaturation and human red blood cell (HRBC) membrane stabilization methods. The extract at different concentrations showed significant percent inhibition of albumin denaturation and percent inhibition of haemolysis when compared with the standard. Thus, the result indicates that the chloroform extract exhibited significant potential on anti-inflammatory and antioxidant activities.

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来源期刊

科技视界

自引率

0.00%

发文量

59577

期刊介绍： Science & Technology Vision is a science and technology journal supervised by the Shanghai Association for Science and Technology and sponsored by the Shanghai Science Writers Association. It takes grassroots science and education workers as readers, popularizes scientific knowledge, tracks hot issues in science and technology at home and abroad, pays attention to new developments, new technologies, and new achievements in the forefront of the science and technology community, adheres to the combination of theory and practice, popularization and exploration, integrates scientificity, knowledge, academicity, and foresight, and builds a platform and theoretical position for academic debate for the majority of science and technology workers. Science & Technology Vision has been fully included in "China National Knowledge Infrastructure", "Chinese Science and Technology Journal (VIP) Database", "Longyuan Journal Network", "Education Reading Network", and "Wanfang Database".