花生过敏儿童益生菌和花生口服免疫治疗后对花生的纵向抗体反应

Clinical & Experimental Allergy Pub Date : 2022-04-11 DOI:10.1111/cea.14146

Kuang-Chih Hsiao, A. Ponsonby, S. Ashley, C. Lee, L. Jindal, M. Tang

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引用次数: 4

摘要

益生菌和花生口服免疫疗法(PPOIT)在治疗结束时诱导持续无反应(SU)是有效的，这种效果在治疗后持续4年，被称为持久性SU。我们试图评估(i) PPOIT如何改变花生特异性体液免疫指数，以及(ii)这些纵向指数如何与持久性SU相关。

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Longitudinal antibody responses to peanut following probiotic and peanut oral immunotherapy in children with peanut allergy

Probiotic and Peanut Oral Immunotherapy (PPOIT) is effective at inducing sustained unresponsiveness (SU) at end‐of‐treatment and this effect persists up to 4 years post‐treatment, referred to as persistent SU. We sought to evaluate (i) how PPOIT altered peanut‐specific humoral immune indices, and (ii) how such longitudinal indices relate to persistent SU.

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Clinical & Experimental Allergy

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