{"title":"社区获得性脑膜炎脊髓灰质炎疫苗病毒神经链基因组序列的还原","authors":"Zenichiro Kato, Y. Shimada, H. Ishiko, N. Kondo","doi":"10.2174/1874309900903010031","DOIUrl":null,"url":null,"abstract":"Neurologic complication associated with the use of live attenuated oral poliomyelitis vaccine is uncommon, but vaccine-associated paralytic poliomyelitis in recipients or contacts has sometimes been reported. We report here a com- munity-acquired aseptic meningitis case and the genetic investigation of the isolated poliovirus type 2. The results of the genetic analysis indicate that the mechanism of this meningitis could be the result of the reversion of the virus during rep- lication in the other vaccine recipients, suggesting a quest for revising the current vaccination program.","PeriodicalId":89037,"journal":{"name":"The open pediatric medicine journal","volume":"87 1","pages":"31-32"},"PeriodicalIF":0.0000,"publicationDate":"2009-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reversion to the Neurovilurent Genome Sequence of Polio Vaccine VirusIsolated from Community-Acquired Meningitis\",\"authors\":\"Zenichiro Kato, Y. Shimada, H. Ishiko, N. Kondo\",\"doi\":\"10.2174/1874309900903010031\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Neurologic complication associated with the use of live attenuated oral poliomyelitis vaccine is uncommon, but vaccine-associated paralytic poliomyelitis in recipients or contacts has sometimes been reported. We report here a com- munity-acquired aseptic meningitis case and the genetic investigation of the isolated poliovirus type 2. The results of the genetic analysis indicate that the mechanism of this meningitis could be the result of the reversion of the virus during rep- lication in the other vaccine recipients, suggesting a quest for revising the current vaccination program.\",\"PeriodicalId\":89037,\"journal\":{\"name\":\"The open pediatric medicine journal\",\"volume\":\"87 1\",\"pages\":\"31-32\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-03-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The open pediatric medicine journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874309900903010031\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The open pediatric medicine journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874309900903010031","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Reversion to the Neurovilurent Genome Sequence of Polio Vaccine VirusIsolated from Community-Acquired Meningitis
Neurologic complication associated with the use of live attenuated oral poliomyelitis vaccine is uncommon, but vaccine-associated paralytic poliomyelitis in recipients or contacts has sometimes been reported. We report here a com- munity-acquired aseptic meningitis case and the genetic investigation of the isolated poliovirus type 2. The results of the genetic analysis indicate that the mechanism of this meningitis could be the result of the reversion of the virus during rep- lication in the other vaccine recipients, suggesting a quest for revising the current vaccination program.
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