老年患者感染模式和抗菌药物敏感性:基于长期护理的研究

Amira H Mahmoud, Abdelwahab E Younes
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引用次数: 0

摘要

目的:本研究旨在确定沙特阿拉伯东部省一家三级医院住院长期护理老年患者的感染模式和抗菌药物敏感性,以指导抗生素使用的基本原理和预防耐药性。材料与方法:从沙特阿拉伯东部省份达曼市某三级医院长期护理的100例≥60岁的老年患者中采集100例标本。收集感染压疮患者尿液标本40份、痰液标本40份、拭子标本20份,进行细菌培养和药敏试验,采用常规方法测定细菌种类,培养48 h后采用纸片扩散法测定细菌的药敏规律。结果:在100份培养标本中,共检出病原菌118种,其中革兰氏阴性菌最多,以肺炎克雷伯菌(32.2%)次之,其次为铜绿假单胞菌(20.3%),其次为人不动杆菌(14.4%)。多药耐药病原菌检出率最高的是不动杆菌(60%),其次是假单胞菌(35%),最后是大肠杆菌(33%)。不同病原菌对抗生素的敏感性存在差异,革兰氏阴性病原菌对氨基苷类和碳青霉烯类的敏感性普遍较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Patterns of infections and antimicrobial susceptibility in elderly patients: Long term care based study
Objective: This study has been conducted to determine Patterns of infections and antimicrobial susceptibility in elderly patients admitted to long term care at a tertiary care hospital in Saudi Arabia, Eastern province to guide rationale for antibiotic use and prevent resistance. Materials & Methods: A total of 100 specimens were collected from100 elderly patients ≥ 60years, both males and females admitted to long term care in a tertiary hospital in Dammam city, Eastern province, Saudi Arabia during the year 2022. Collected specimens included forty urine samples , forty sputum samples and twenty swabs from infected pressure ulcers .All collected specimens were sent for bacterial culture and sensitivity, bacterial species were determined by conventional methods and disk diffusion was used to determine the antimicrobial susceptibility pattern of the bacteria isolates after 48 hours incubation. Results: Out of the 100 cultured specimens, 118 pathogens were detected in the whole sample where Gram-negative bacteria: primarily, Klebsiella pneumoniae (32.2%) followed by pseudomonas aeruginosa (20.3%) then Acinetobacter bumannii (14.4%) represented the most prevalent pathogens. High percentage of multidrug resistant pathogens (MDR) was detected mostly among Acinetobacter 60% followed by pseudomonas 35% then E-coli 33%. Antibiotic sensitivity was variable among different pathogens, gram negative pathogens sensitivity was generally high mainly to amino glycosides and carbapenems groups.
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