生殖/发育毒性筛选试验(OECD TG 421)和结合重复剂量毒性研究与生殖/发育毒性筛选试验(OECD TG 422)

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引用次数: 1

摘要

重量:(仅限亲本)睾丸、附睾、前列腺和精囊及凝固腺(OECD TG 421和TG 422),加上肾上腺(OECD TG 422)。可选的器官重量包括提肛肌加球海绵体肌肉复合体,男性阴茎的考伯氏腺和龟头,成对的卵巢和子宫(包括子宫颈)。所有成年犬和PND 13幼崽(OECD TG 421和TG 422)的甲状腺重量(固定后)均可测量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Reproduction/Developmental Toxicity Screening Test (OECD TG 421) and Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (OECD TG 422)
Weights of: (parents only) testes, epididymides, prostate and seminal vesicles with coagulating glands (OECD TG 421 and TG 422), plus adrenals (OECD TG 422 only). Optional organ weights could include levator ani plus bulbocavernosus muscle complex, Cowper’s glands and glans penis in males, and paired ovaries and uterus (including cervix). Thyroid gland weight could be measured (after fixation) in all adults and PND 13 pups (OECD TG 421 and TG 422).
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