使用 R 管道的间接参考区间。

IF 0.6 1区历史学 0 ARCHAEOLOGY

JOURNAL OF NEAR EASTERN STUDIES Pub Date : 2022-02-23 eCollection Date: 2022-04-01 DOI:10.1016/j.jmsacl.2022.02.004

Dustin R Bunch

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引用次数: 0

摘要

背景：间接参考区间需要稳健的统计方法来区分病理值和健康值。使用 R（一种免费提供的统计编程语言）创建的数据管道可以实现这一目标：方法：利用 NHANES 的数据集创建了一个数据管道，用于睾酮（Testo；n = 7207）和天门冬氨酸氨基转移酶（AST；n = 5882）的摄取、分区、归一化、去除异常值并确定参考区间：该管道确定的 AST 和 Testo 估计值接近当前的 RI。在使用该管道时应小心谨慎，因为其局限性取决于分析物的病理学和用于估算 RI 的数据集：结论：R 可用来创建一个稳健的统计参考区间管道。

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Indirect reference intervals using an R pipeline.

Background: Indirect reference intervals require robust statistical approaches to separate the pathological and healthy values. This can be achieved with a data pipeline created in R, a freely available statistical programming language.

Methods: A data pipeline was created to ingest, partition, normalize, remove outliers, and identify reference intervals for testosterone (Testo; n = 7,207) and aspartate aminotransferase (AST; n = 5,882) using data sets from NHANES.

Results: The estimates for AST and Testo determined by this pipeline approximated current RIs. Care should be taken when using this pipeline as there are limitations that depend on the pathology of the analyte and the data set being used for RI estimation.

Conclusions: R can be used to create a robust statistical reference interval pipeline.

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来源期刊

JOURNAL OF NEAR EASTERN STUDIES Multiple-

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Devoted to an examination of the civilizations of the Near East, the Journal of Near Eastern Studies has for 125 years published contributions from scholars of international reputation on the archaeology, art, history, languages, literatures, and religions of the Near East. Founded in 1884 as Hebraica, the journal was renamed twice over the course of the following century, each name change reflecting the growth and expansion of the fields covered by the publication. In 1895 it became the American Journal of Semitic Languages and Literatures, and in 1942 it received its present designation, the Journal of Near Eastern Studies. From an original emphasis on Old Testament studies in the nineteenth century.