基于波导的便携式光学生物传感器

IF 1.8 3区社会学 Q1 SOCIAL WORK

British Journal of Social Work Pub Date : 2022-03-25 DOI:10.3390/bios12040195

Philip A Kocheril, Kiersten D Lenz, David D L Mascareñas, John E Morales-Garcia, Aaron S Anderson, Harshini Mukundan

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引用次数: 0

摘要

快速的现场诊断可为作战人员支持、环境监测和全球健康需求提供及时的干预和响应。便携式光学生物传感器因其潜在的光学检测速度和准确性，正被广泛用作实现现场生物传感的一种手段。我们最近开发了便携式自动采样工程分析传感器（PEGASUS），目的是开发一种可现场使用的通用生物传感平台。在此，我们将详细介绍 PEGASUS 传感硬件的开发过程，并使用一个由相同传感硬件和软件组成的测试平台系统演示如何通过生物素-链霉亲和素化学反应检测 1 nM 的荧光共轭物。

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Portable Waveguide-Based Optical Biosensor.

Rapid, on-site diagnostics allow for timely intervention and response for warfighter support, environmental monitoring, and global health needs. Portable optical biosensors are being widely pursued as a means of achieving fieldable biosensing due to the potential speed and accuracy of optical detection. We recently developed the portable engineered analytic sensor with automated sampling (PEGASUS) with the goal of developing a fieldable, generalizable biosensing platform. Here, we detail the development of PEGASUS's sensing hardware and use a test-bed system of identical sensing hardware and software to demonstrate detection of a fluorescent conjugate at 1 nM through biotin-streptavidin chemistry.

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来源期刊

British Journal of Social Work SOCIAL WORK-

CiteScore

3.00

自引率

22.20%

发文量

208

期刊介绍： Published for the British Association of Social Workers, this is the leading academic social work journal in the UK. It covers every aspect of social work, with papers reporting research, discussing practice, and examining principles and theories. It is read by social work educators, researchers, practitioners and managers who wish to keep up to date with theoretical and empirical developments in the field.