水生有害物质生态毒理学评价的实地研究

C. Kussatz
{"title":"水生有害物质生态毒理学评价的实地研究","authors":"C. Kussatz","doi":"10.1002/TOX.2530090405","DOIUrl":null,"url":null,"abstract":"The role of field tests for chemical management must not be overestimated. Results obtained from multi species tests in the field indisputably give valuable information on the fate of a substance that facilitates the assessment of results from laboratory tests provided the test design is orientated on the appropriate formulation of question. \n \n \n \nIf those investigations are available, they are included in the assessment of substances. These may increase the uncertainty factor, but this can only be a critical case-by-case decision. \n \n \n \nThe investigations, however, have to satisfy certain minimum requirements: \n \n \n \n—examination of several test concentrations and untreated controls, proof of a dose–effect relationship, ability to derive the NOEC; \n \n \n \n \n—exposure of several taxonomic groups over a longer period; \n \n \n \n \n—analytical control of the test concentration during the experiment; \n \n \n \n \n—equivalent development of controls, ability to repeat the experiments under different starting conditions; and \n \n \n \n \n—use of aquatic ecological parameters as toxicological end points. \n \n \n \n \n \n \nIndependently of these requirements, the necessity of validation does in principle exist. © 1994 by John Wiley & Sons, Inc..","PeriodicalId":11824,"journal":{"name":"Environmental Toxicology & Water Quality","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1994-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Aquatic field studies in ecotoxicological assessment of hazardous substances\",\"authors\":\"C. Kussatz\",\"doi\":\"10.1002/TOX.2530090405\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The role of field tests for chemical management must not be overestimated. Results obtained from multi species tests in the field indisputably give valuable information on the fate of a substance that facilitates the assessment of results from laboratory tests provided the test design is orientated on the appropriate formulation of question. \\n \\n \\n \\nIf those investigations are available, they are included in the assessment of substances. These may increase the uncertainty factor, but this can only be a critical case-by-case decision. \\n \\n \\n \\nThe investigations, however, have to satisfy certain minimum requirements: \\n \\n \\n \\n—examination of several test concentrations and untreated controls, proof of a dose–effect relationship, ability to derive the NOEC; \\n \\n \\n \\n \\n—exposure of several taxonomic groups over a longer period; \\n \\n \\n \\n \\n—analytical control of the test concentration during the experiment; \\n \\n \\n \\n \\n—equivalent development of controls, ability to repeat the experiments under different starting conditions; and \\n \\n \\n \\n \\n—use of aquatic ecological parameters as toxicological end points. \\n \\n \\n \\n \\n \\n \\nIndependently of these requirements, the necessity of validation does in principle exist. © 1994 by John Wiley & Sons, Inc..\",\"PeriodicalId\":11824,\"journal\":{\"name\":\"Environmental Toxicology & Water Quality\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1994-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Environmental Toxicology & Water Quality\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/TOX.2530090405\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Toxicology & Water Quality","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/TOX.2530090405","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

现场试验对化学品管理的作用绝不能被高估。从实地多物种试验中获得的结果无疑提供了关于某种物质命运的宝贵信息,有助于评估实验室试验的结果,只要试验设计以问题的适当表述为导向。如果这些调查是可用的,它们将包括在物质评估中。这些可能会增加不确定性因素,但这只能是一个关键的个案决定。然而,调查必须满足某些最低要求:-检查几种测试浓度和未经处理的对照,证明剂量效应关系,能够得出NOEC;-几个分类类群在较长时期内的暴露;-实验过程中测试浓度的分析控制;-等效开发对照,能够在不同启动条件下重复实验;并采用水生生态参数作为毒理学终点。独立于这些要求之外,验证的必要性在原则上确实存在。©1994 by John Wiley & Sons, Inc.。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aquatic field studies in ecotoxicological assessment of hazardous substances
The role of field tests for chemical management must not be overestimated. Results obtained from multi species tests in the field indisputably give valuable information on the fate of a substance that facilitates the assessment of results from laboratory tests provided the test design is orientated on the appropriate formulation of question. If those investigations are available, they are included in the assessment of substances. These may increase the uncertainty factor, but this can only be a critical case-by-case decision. The investigations, however, have to satisfy certain minimum requirements: —examination of several test concentrations and untreated controls, proof of a dose–effect relationship, ability to derive the NOEC; —exposure of several taxonomic groups over a longer period; —analytical control of the test concentration during the experiment; —equivalent development of controls, ability to repeat the experiments under different starting conditions; and —use of aquatic ecological parameters as toxicological end points. Independently of these requirements, the necessity of validation does in principle exist. © 1994 by John Wiley & Sons, Inc..
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信