羟钴胺治疗与儿童偏头痛残疾评估量表评分

IF 0.2 Q4 PEDIATRICS

Journal of pediatric neurology Pub Date : 2022-07-11 DOI:10.1055/s-0042-1750796

Senem Ayça, Ceren Dogan

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引用次数: 0

摘要

偏头痛是儿童，尤其是青少年常见的神经系统疾病。它会影响学习表现、家庭和社会日常活动。儿童偏头痛残疾评估量表(PedMIDAS)通常用于年轻患者。本研究评估了偏头痛儿童的维生素B12缺乏症以及羟钴胺素治疗对PedMIDAS评分的影响。研究小组包括维生素B12缺乏症和诊断为偏头痛的患者。在治疗前和治疗后3个月进行PedMIDAS问卷调查。对治疗前后的PedMIDAS评分进行评价和比较。偏头痛患儿维生素B12水平的平均值±标准差为175.9±21.3 pg/mL。羟钴胺治疗后PedMIDAS评分明显低于治疗前(p < 0.001)。这些结果表明，羟钴胺素对缓解儿童偏头痛症状有积极作用，治疗维生素B12缺乏症可能是一种有用的选择。

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Hydroxocobalamin Treatment and Pediatric Migraine Disability Assessment Scale Scores

Migraine is a common neurologic disorder in children, especially in adolescents. It can affect the school performance, family, and social daily activities. The Pediatric Migraine Disability Assessment Scale (PedMIDAS) is commonly used in young patients. This study evaluated vitamin B12 deficiency in children with migraine and the effect of hydroxocobalamin treatment on PedMIDAS scores. The study group comprised patients with vitamin B12 deficiency and diagnosed migraine. The PedMIDAS questionnaire was conducted before and 3 months after hydroxocobalamin treatment. PedMIDAS scores were evaluated and compared before and after hydroxocobalamin treatment. The mean ± standard deviation of vitamin B12 level was 175.9 ± 21.3 pg/mL in children with migraine. The PedMIDAS scores were significantly lower after hydroxocobalamin treatment than before treatment (p < 0.001). These results indicated that hydroxocobalamin made a positive contribution to the mitigation of migraine symptoms in children and that treating vitamin B12 deficiency could be a useful option.

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来源期刊

Journal of pediatric neurology PEDIATRICS-

CiteScore

0.40

自引率

0.00%

发文量

期刊介绍： The Journal of Pediatric Neurology is a multidisciplinary peer-reviewed medical journal publishing articles in the fields of childhood neurology, pediatric neurosurgery, pediatric neuroradiology, child psychiatry and pediatric neuroscience. The Journal of Pediatric Neurology, the official journal of the Society of Pediatric Science of the Yüzüncü Yil University in Turkiye, encourages submissions from authors throughout the world. The following articles will be considered for publication: editorials, original and review articles, rapid communications, case reports, neuroimage of the month, letters to the editor and book reviews.