雌性小鼠海马齿状回神经发生与性激素水平的关系

P. Dana, Ghorbanian Mt
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引用次数: 1

摘要

背景:雌性小鼠在发情周期中性激素的正常波动影响海马神经发生。海马体还包含许多类固醇受体,提示性激素对海马体可塑性的调节作用。海马结构和功能水平上的性别差异主要是由于发情周期中类固醇激素的波动。本研究旨在探讨发情周期不同阶段血清性激素水平与胶质原纤维酸性蛋白(GFAP)表达的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neurogenesis in the Dentate Gyrus of the Hippocampus Associated with Sex Hormone Levels in Female Mice
Background: Usual fluctuations of sex hormones during the estrous cycle in female mice affect the hippocampal neurogenesis. The hippocampus also comprises many steroid receptors suggesting the modulatory effects of gonadal hormones on the hippocampal plasticity. Sex differences at the level of structure and function of the hippocampus are mostly due to the fluctuations of steroid hormones during the estrous cycle. The purpose of this study was to investigate relationship with serum sex hormone levels and the expression of glial fibrillary acidic protein (GFAP) at different phases of the estrous cycle.
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