硫代氨基脲的磷酸化

IF 1.1 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY
S. Baird, C. Vogels, S. Geier, Lara K. Watanabe, J. Binder, C. L. Macdonald, S. Westcott
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引用次数: 0

摘要

本研究报道了几种硫代氨基脲(R5R4NC(S)NR3N=CR1R2)的磷酸化反应的探索。Ph2PBpin (pin = 1,2- o2c2me4)或Ph2PBcat (cat = 1,2- o2c6h4)与含有末端伯胺或仲胺的硫代氨基脲发生反应,可产率高的含硼杂环1,3,4-噻二唑啉产物。将Ph2PBpin加入到末端含有NMe2基团的硫代氨基脲中,生成了含硼、硫和氮原子的中等产率的新型五元杂环。硫代氨基脲类化合物的杂环化优先发生在乙酰基和吡啶基等官能团的存在下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The phosphinoboration of thiosemicarbazones
This study reports on the exploration of the phosphinoboration reaction with several thiosemicarbazones (R5R4NC(S)NR3N=CR1R2). Reactions between either Ph2PBpin (pin = 1,2-O2C2Me4) or Ph2PBcat (cat = 1,2-O2C6H4) with thiosemicarbazones containing a terminal primary or secondary amine afforded boron-containing heterocyclic 1,3,4-thiadiazoline products in excellent yield. The addition of Ph2PBpin to thiosemicarbazones containing an NMe2 group in the terminal position generated novel five-membered heterocycles in moderate yield, which included boron, sulfur, and nitrogen atoms. Heterocyclization of the thiosemicarbazones occurs preferentially in the presence of functional groups such as acetyl and pyridyl groups.
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来源期刊
Canadian Journal of Chemistry
Canadian Journal of Chemistry 化学-化学综合
CiteScore
1.90
自引率
9.10%
发文量
99
审稿时长
1 months
期刊介绍: Published since 1929, the Canadian Journal of Chemistry reports current research findings in all branches of chemistry. It includes the traditional areas of analytical, inorganic, organic, and physical-theoretical chemistry and newer interdisciplinary areas such as materials science, spectroscopy, chemical physics, and biological, medicinal and environmental chemistry. Articles describing original research are welcomed.
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