痴呆:基于Tau蛋白变化的神经病理学

Bedadyuti Mohanty
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引用次数: 0

摘要

痴呆症是一种临床情况,需要基于动态记忆失败和主观丧失的新的实际依赖,正如其拉丁语来源所提出的那样:从过去的精神功能中退出。痴呆症的发病率随着年龄的增长而上升,使其成为成熟人群中不可否认的共同主题。痴呆症患者的表现在社会和身心健康方面都更加依赖和无助,给社会、医疗服务和医院带来了更大的困难。尽管这个假设看起来直截了当,但对痴呆症的临床分析可能会很麻烦,因为新生的功能残疾常常被身体虚弱和痛苦所笼罩。痴呆的临床基础和神经学基础有明显的重叠。症状的发展将我们带进了病理生理过程的障碍集中治疗。大量的研究活动正在进行中,以在疾病发生之前区分潜在的生物标志物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dementia: Neuropathology Based on Changes in Tau Protein
Dementia is a clinical situation that requires novel practical dependence based on the dynamic memory failure and subjective loss, as its Latin source proposes: an exit from past mental functioning. The occurrence of dementia ascends with age, making it an undeniably common subject among the matured populace. The nature of manifestations among individuals with dementia is more dependent and helpless, both socially and regarding physical and psychological wellness, introducing advancing difficulties to society and to our medical services and hospitals. In spite of the apparently straightforward premise, the clinical analysis of dementia can be troublesome with de novo functional disability frequently clouded by physical weakness and misery. Clinical and neurotic basis for the fundamental dementia causing illnesses overlaps remarkably. The development of symptoms takes us into the patho-physiological procedure hamper focused on disorder treatment. An incredible number of research activities are in progress to distinguish potential biomarkers of disease prior its occurrence.
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