应用6-氨基己酸(eaca)减少二尖瓣置换术后出血

中国医师进修杂志 Pub Date : 2001-05-15 DOI:10.3760/CMA.J.ISSN.1673-4904.2001.05.009

Du Zheng-long, Kuang Zhu-sheng, Xiong Rong-sheng, W. Zhi-gang, Liu Yi-bo, Xiao Hong-tao, B. Tao, Deng Sheng, Z. Fu

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引用次数: 0

摘要

目的探讨6-氨基己酸(EACA)对二尖瓣置换术后出血的影响。方法50例成人二尖瓣置换术患者采用双双随机对照试验，随机分为两组。每组25例。对照组患者给予NS治疗，研究组患者给予与对照组相同的NS治疗，但经静脉注射加入EACE 10 g。分别于术后第6、24小时记录胸腔内出血量及ACT。结果各研究组术后第6 h出血量为(290.0±41.3)ml，第24 h出血量为(336.3±81.3)ml，对照组术后第6 h出血量为(393.4±73.6)ml，第24 h出血量为(450.0±79.6)ml，各研究组出血量均较对照组明显减少(P0.05)。结论:6-氨基己酸可减少二尖瓣置换术后出血。

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THE USE OF 6-AMINOCAPROIC ACID (EACA) TO REDUCE POSTOPERATIVE BLEEDING FOLLOWING IN MITRAL VALVE REPLACEMENT

Objective\ To determine the effect of 6-aminocaproic acid (EACA) to reduce postoperation bleeding following in mitral valve replacement.Method\ 50 adult patients uddergoing mitral valve replacement was adopted a double-bisind randomized trial to be divided into two groups.Each group is 25 patients.The patients in control groups received NS,the ones in study groups received NS as same as control groups but added EACE 10 g by intravation.The bleeding amount in cavitas thoracis were recorded on the sixth,twenty-fourth postoperative hours and ACT was recorded as well.Results\ The bleeding amount in study groups on the sixth postoperative hours were (290.0±41.3) ml.On twenty-fourth postoperative hours were (336.3±81.3) ml.The bleeding amount in control groups on the sixth postoperative hours were (393.4±73.6) ml.On twenty-fourth postoperative hours were (450.0±79.6) ml.The bleeding amount in study groups were decreased significantly as compared with in control groups (P0.05).Conclusion:6-aminocaproic acid can reduce postoperation bleeding following in mitral valve replacement.

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来源期刊

中国医师进修杂志

自引率

0.00%

发文量

26239

期刊介绍： Chinese Journal of Postgraduates of Medicine (founded in 1978, monthly) is one of the series of journals of the Chinese Medical Association (CMA) under the supervision of the National Health Commission of the People's Republic of China, sponsored by the Chinese Medical Association (CMA) and Dalian Institute of Theoretical Medicine (DITM). It is a core journal of Chinese science and technology, a statistical source journal of Chinese scientific and technical papers, and a statistical source journal of China Academic Journal Impact Factor Annual Report. The journal adheres to the purpose of using continuing medical education and post training, highlights new theories, new knowledge, new methods and new technologies, and focuses on the combination of theory and practice, and the combination of popularisation and improvement. Main columns: Special tutorials, expert forums, clinical treatises, clinical experience, reviews and lectures, continuing medical education, teaching and research, advanced training forum, drugs and clinics, overview of progress, introduction of new technologies, imaging and clinics, lessons learnt, discussions and evaluations, case reports, discussions of clinical cases, conference proceedings, and domestic and international academic developments. The main target readers are clinical medical personnel in internal medicine, surgery, gynaecology, paediatrics and ophthalmology.