探讨采用含乙醇湿巾采血测定酒精浓度的效果

T. Nakao, Atsushi Nitta, H. Nishioka, M. Katagi, Noriko Tsuda, Yasuhide Kitazawa
{"title":"探讨采用含乙醇湿巾采血测定酒精浓度的效果","authors":"T. Nakao, Atsushi Nitta, H. Nishioka, M. Katagi, Noriko Tsuda, Yasuhide Kitazawa","doi":"10.4236/PP.2021.1210018","DOIUrl":null,"url":null,"abstract":"This study was aimed to establish whether the skin \npreparation using ethanol-containing skin antiseptics causes ethanol \ncontamination through blood collection. Venous blood was collected from 40 healthy \nvolunteers according to the national guidelines for blood sampling, with four \nsequential procedures as follows: 1) collecting blood immediately (within 5 \nseconds) after cleaning the skin with an individually packaged type of \nethanol-containing wipe, 2) collecting blood 1 minute after cleaning the skin \nwith an individually packaged type of ethanol-containing wipe, 3) collecting \nimmediately (within 5 seconds) after cleaning the skin with a traditional \ncleaning method (thoroughly ethanol-impregnated wipe, and 4) collecting 1 \nminute after cleaning the skin with a traditional cleaning method. Each \nsequential procedure was performed with and \nwithout the ethanol-containing wipe used for skin cleaning on the \npuncture site on their right and left arms at the time the needle was \nwithdrawn, respectively. The collected specimens were subjected to the \ndetermination of ethanol by using headspace gas chromatography-mass \nspectrometry. In every 80 blood specimens obtained from 40 participants, \nethanol was undetectable (<0.001 mg/mL). This study demonstrates that \ndisinfection using ethanol-containing skin antiseptics is unlikely to cause \nethanol contamination through blood collection regardless of skin preparation \ntechnique according to the guidelines for blood sampling. This may have \nimplications in forensic science.","PeriodicalId":19875,"journal":{"name":"Pharmacology & Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"To Investigate the Effect of Using Ethanol Containing Wipes in Collecting Blood for the Measurement of Alcohol Concentration\",\"authors\":\"T. Nakao, Atsushi Nitta, H. Nishioka, M. Katagi, Noriko Tsuda, Yasuhide Kitazawa\",\"doi\":\"10.4236/PP.2021.1210018\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study was aimed to establish whether the skin \\npreparation using ethanol-containing skin antiseptics causes ethanol \\ncontamination through blood collection. Venous blood was collected from 40 healthy \\nvolunteers according to the national guidelines for blood sampling, with four \\nsequential procedures as follows: 1) collecting blood immediately (within 5 \\nseconds) after cleaning the skin with an individually packaged type of \\nethanol-containing wipe, 2) collecting blood 1 minute after cleaning the skin \\nwith an individually packaged type of ethanol-containing wipe, 3) collecting \\nimmediately (within 5 seconds) after cleaning the skin with a traditional \\ncleaning method (thoroughly ethanol-impregnated wipe, and 4) collecting 1 \\nminute after cleaning the skin with a traditional cleaning method. Each \\nsequential procedure was performed with and \\nwithout the ethanol-containing wipe used for skin cleaning on the \\npuncture site on their right and left arms at the time the needle was \\nwithdrawn, respectively. The collected specimens were subjected to the \\ndetermination of ethanol by using headspace gas chromatography-mass \\nspectrometry. In every 80 blood specimens obtained from 40 participants, \\nethanol was undetectable (<0.001 mg/mL). This study demonstrates that \\ndisinfection using ethanol-containing skin antiseptics is unlikely to cause \\nethanol contamination through blood collection regardless of skin preparation \\ntechnique according to the guidelines for blood sampling. This may have \\nimplications in forensic science.\",\"PeriodicalId\":19875,\"journal\":{\"name\":\"Pharmacology & Pharmacy\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-10-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmacology & Pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4236/PP.2021.1210018\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacology & Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4236/PP.2021.1210018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

本研究旨在确定使用含乙醇皮肤防腐剂的皮肤制剂是否会通过采血引起乙醇污染。根据国家采血指南采集40名健康志愿者静脉血,按以下4个步骤依次进行:1)使用单独包装的含乙醇擦拭器清洁皮肤后立即(5秒内)采集血液,2)使用单独包装的含乙醇擦拭器清洁皮肤1分钟后立即采集血液,3)使用传统清洁方法(彻底浸渍乙醇擦拭)清洁皮肤后立即(5秒内)采集血液,4)使用传统清洁方法清洁皮肤1分钟后采集血液。每个顺序的程序分别使用和不使用含乙醇的擦拭剂进行,该擦拭剂用于在拔针时清洁右手臂和左臂穿刺部位的皮肤。收集的样品采用顶空气相色谱-质谱法测定乙醇含量。从40名参与者中获得的每80份血液标本中,未检测到乙醇(<0.001 mg/mL)。本研究表明,根据采血指南,无论采用何种皮肤制备技术,使用含乙醇的皮肤防腐剂进行消毒都不太可能通过采血造成乙醇污染。这可能会对法医学产生影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
To Investigate the Effect of Using Ethanol Containing Wipes in Collecting Blood for the Measurement of Alcohol Concentration
This study was aimed to establish whether the skin preparation using ethanol-containing skin antiseptics causes ethanol contamination through blood collection. Venous blood was collected from 40 healthy volunteers according to the national guidelines for blood sampling, with four sequential procedures as follows: 1) collecting blood immediately (within 5 seconds) after cleaning the skin with an individually packaged type of ethanol-containing wipe, 2) collecting blood 1 minute after cleaning the skin with an individually packaged type of ethanol-containing wipe, 3) collecting immediately (within 5 seconds) after cleaning the skin with a traditional cleaning method (thoroughly ethanol-impregnated wipe, and 4) collecting 1 minute after cleaning the skin with a traditional cleaning method. Each sequential procedure was performed with and without the ethanol-containing wipe used for skin cleaning on the puncture site on their right and left arms at the time the needle was withdrawn, respectively. The collected specimens were subjected to the determination of ethanol by using headspace gas chromatography-mass spectrometry. In every 80 blood specimens obtained from 40 participants, ethanol was undetectable (<0.001 mg/mL). This study demonstrates that disinfection using ethanol-containing skin antiseptics is unlikely to cause ethanol contamination through blood collection regardless of skin preparation technique according to the guidelines for blood sampling. This may have implications in forensic science.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信