类固醇滥用、生活质量和皮肤癣的各种危险因素:来自印度北部三级保健中心的横断面观察研究。

IF 0.6 Q4 DERMATOLOGY
Dilip Meena, N. Hazarika, P. Chauhan, Pratika Goyal
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引用次数: 1

摘要

皮肤真菌病是一种浅表皮肤真菌病,在印度正在稳步发展为流行病。各种因素,如类固醇的过度使用和误用,目前使其治疗具有挑战性。该研究考察了皮肤癣患者的各种社会人口学特征、临床因素和类固醇滥用情况,并评估了他们的生活质量(QOL)。方法在获得知情书面同意后,对患有皮肤癣的成年患者进行为期1年的医院横断面研究。记录社会人口学和临床细节,用皮肤病生活质量指数(DLQI)问卷评估生活质量。结果550例患者中,最常见的皮肤病是癣(n = 408/550, 74.18%),以股癣和体癣为主。类固醇滥用较多(n = 511/550, 92.90%),最常见的是丙酸氯倍他索(n = 26/ 52,50%)。最常见的副作用是色素减退和萎缩(53.52%)。男性DLQI平均值为14.44±7.29,女性为15.78±6.26。DLQI评分受类固醇滥用、低社会经济地位、年轻成人地位、广泛的癣和卫生条件差的影响(p < 0.05)。结论皮肤真菌病对生活质量有明显的不良影响。正如在这项研究中所看到的,类固醇的广泛滥用可能是印度出现顽固性癣的主要原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Steroid abuse, quality of life, and various risk factors in dermatophytosis: a cross-sectional observational study from a tertiary care center in northern India.
INTRODUCTION Dermatophytosis is a superficial cutaneous mycosis and is steadily progressing to epidemic proportions in India. Various factors such as steroid overuse and misuse are currently making its treatment challenging. The study examines various sociodemographic characteristics, clinical factors, and steroid abuse in patients with dermatophytosis and also assess their quality of life (QOL). METHODS A hospital‑based cross‑sectional study was carried out for a period of 1 year among adult patients with dermatophytosis after obtaining informed written consent. Sociodemographic and clinical details were recorded, and QOL was assessed with the Dermatology Life Quality Index (DLQI) questionnaire. RESULTS Among 550 patients analyzed, the most common dermatophytosis was tinea (n = 408/550, 74.18%), dominated by tinea cruris and tinea corporis. Steroid abuse was frequent (n = 511/550, 92.90%), the most common being clobetasol propionate (n = 26/52, 50%). Hypopigmentation and atrophy were the most common side effects (53.52%). The mean DLQI was 14.44 ± 7.29 in males and 15.78 ± 6.26 in females. DLQI scores were statistically influenced (p < .05) by steroid abuse, low socioeconomic status, young adult status, widespread tinea, and poor hygiene. CONCLUSION Dermatophytosis was found to have a significant adverse impact on QOL. As seen in this study, the widespread abuse of steroids may be a leading cause of the emergence of recalcitrant tinea in India.
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来源期刊
CiteScore
1.70
自引率
8.30%
发文量
38
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