急性淋巴母细胞白血病中与白细胞病综合征相关的阻塞性休克:病例报告

Misael Moreno-Trujillo , Edmundo Israel Roque-Márquez , Elliot Valle-Rodríguez , Erika Nallely Orendain-Jaime
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引用次数: 0

摘要

急性淋巴细胞白血病是儿科人群中一种常见的恶性疾病,仅占成人白血病病例的20%。在急性淋巴细胞白血病患者中,白细胞增多症的发展与更高的死亡率有关。虽然它最常影响的器官是脑和肺,但本病例表现为阻塞性休克,是病情的加重情况。该病例患者为32岁女性,患有乏力和动力不足,入院时已持续2周,后来伴有恶心和呕吐。患者无其他潜在的慢性退行性疾病。在她进入急诊科时,患者有65.2万个白细胞,单核细胞差异为48万个,未成熟细胞占88%。她有多器官衰竭的临床症状。本病例是基于其有害的结果,随着多器官功能障碍的发展,加重的情况下,由白细胞增多引起的阻塞性休克导致心力衰竭。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Choque obstructivo asociado a síndrome de leucostasis en leucemia linfoblástica aguda: reporte de caso

Acute lymphoblastic leukaemia is a common malignant disorder in the paediatric population that occurs in just 20% of leukaemia cases in the adult population. The development of hyperleukocytosis is linked to greater mortality in patients with acute lymphoblastic leukaemia. Although the organs it most commonly affects are the brain and lungs, this case presented obstructive shock as an aggravating circumstance of the condition. The patient in this case is a 32-year-old woman suffering from asthenia and adynamia, which had been ongoing for 2 weeks on admission to hospital, and which was latterly accompanied by nausea and vomiting. The patient had no other underlying chronic degenerative disorders. On her admission to the emergency department, the patient had 652,000 leukocytes, with a monocyte differential of 480,000 and 88% immature cells. She had clinical symptoms of multiple organ failure. This case is submitted based on its detrimental outcome with the development of multiple organ dysfunction, with the aggravating circumstance of heart failure resulting from obstructive shock owing to hyperleukocytosis.

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