某大学医院健康人缺血修饰白蛋白水平的参考值

IF 0.6 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
C. Duman, C. Bakar, Ertan Eşsi̇zoğlu, Funda Kirtay Tutunculer, Elif Demircan
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引用次数: 4

摘要

目的:缺血修饰白蛋白(IMA)试验是一种心肌缺血标志物,可用于急性冠脉综合征的诊断。本研究的目的是确定在Canakkale Onsekiz Mart大学录取的15岁以上健康人的IMA测试的参考价值。方法:本研究对在Canakkale Onsekiz Mart大学医学院美容与应用医院就诊的582名15岁以上、外表健康的患者进行了研究。在按年龄组和性别分配研究组时,以土耳其2011年人口为参照。对研究参与者进行了人口统计特征和健康问题调查,并抽取了9cc静脉血。用Bar-Or定义的spect-光度法测定IMA水平。采用平均值、标准差、中位数、最小值、最大值和2.5% - 97.5%的区间来检测IMA参考值。结果:男性274例(47.1%),女性308例(52.9%)。实验组IMA平均值为0.339±0.093,中位数为0.343 (Min-Max为0.053 ~ 0.631),2.5% ~ 97.5%的百分位数为0.145 ~ 0.530。结论:表明IMA诊断缺血性疾病的参考水平的研究是不足的。我们的研究有望有助于缩小这一差距。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The reference values of ischemia modified albumin levels in healthy people admitted to a university hospital
Objectives: The Ischemia Modified Albumin (IMA) test is a myocardial ischemia marker which may have potential use for the diagnosis of Acute Coronary Syndrome. The aim of this study was determine reference values of IMA test on the healthy people over the age of 15 who's admitted to Canakkale Onsekiz Mart University. Methods: This study was performed on 582 people over 15 years old and healthy in appearan- ce who had presented at the Canakkale Onsekiz Mart University Faculty of Medicine Rese- arch and Application Hospital. The year 2011 population of Turkey was taken as the reference in the distribution of the study group according to age group and gender. A survey which queried the demographic features and health problems was administered to the participants of the study and 9 cc venous blood was drawn. IMA levels were measured by using the spect- rophotometric method defined by Bar-Or. The mean, standard deviation, median, minimum, maximum, and 2.5 % - 97.5 % interval were used in order to detect the IMA reference values. Results: A total of 274 males (47.1 %) and 308 women (52.9 %) were studied. The mean IMA value of the examined group was 0.339 ± 0.093, and the median was 0.343 (Min-Max: 0.053- 0.631), while the 2.5 % - 97.5 % percentil values were 0.145 - 0.530. Conclusion: Studies that indicate the reference levels of the IMA for the diagnosis of ische- mic conditions are insufficient. Our study is expected to contribute to closing this gap.
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来源期刊
CiteScore
1.20
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Turkish Journal of Biochemistry (TJB), official journal of Turkish Biochemical Society, is issued electronically every 2 months. The main aim of the journal is to support the research and publishing culture by ensuring that every published manuscript has an added value and thus providing international acceptance of the “readability” of the manuscripts published in the journal.
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