电休克疗法对精神病患者额叶 QRS-T 角的影响

IF 2 2区 数学 Q1 MATHEMATICS, APPLIED
Inverse Problems Pub Date : 2024-05-29 eCollection Date: 2024-01-01 DOI:10.29399/npa.28443
Ülker Atılan Fedai, Halil Fedai
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引用次数: 0

摘要

简介电休克疗法(ECT)是一种生物疗法,具有良好的耐受性和较低的并发症风险。与电休克疗法相关的急性心血管并发症,如室性心律失常、心肌梗塞和心脏骤停,均有记录。额叶 QRS-T 角(fQRS-T)增大与室性心律失常、心脏性猝死和总死亡率有关。在这项研究中,我们旨在通过心电图(ECG)参数,如 fQRS-T 角、QRS 持续时间、QT 和 QTc 间期,评估 ECT 对心肌的影响:本研究共纳入 108 名接受 ECT 治疗的双相情感障碍(36 人)、抑郁障碍(70 人)和精神分裂症(2 人)患者。所有患者在电痉挛疗法前、电痉挛疗法后 15 分钟和电痉挛疗法后 24 小时内均接受了 12 导联表面心电图检查:结果:QRS时程、QT间期和校正QT(QTc)间期在随访期间无明显变化。然而,我们发现,与基线角度相比,电痉挛治疗后 15 分钟,fQRS-T 角度明显增加(p结论:在我们的研究中,观察到 ECT 15 分钟后 fQRS-T 角明显增加。但在 24 小时后,fQRS-T 角度恢复正常。我们的研究结果可能表明,根据 fQRS-T 角度,ECT 不会对心血管事件风险产生永久性副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effect of Electroconvulsive Therapy on Frontal QRS-T Angle in Psychiatric Patients.

Introduction: Electroconvulsive therapy (ECT) is one of the biological therapies that is well tolerated and has a low risk of complications. Acute cardiovascular complications related to ECT such as ventricular arrhythmia, myocardial infarction and cardiac arrest have been recorded. Increased frontal QRS-T (fQRS-T) angle was associated with ventricular arrhythmia, sudden cardiac death and total mortality. In this study, we aimed to evaluate the effect of ECT on the myocardium using electrocardiography (ECG) parameters such as fQRS-T angle, QRS duration, QT and QTc interval.

Methods: A total of 108 patients diagnosed with bipolar disorder (n=36), depressive disorder (n=70) and schizophrenia (n=2) who underwent ECT were included in this study. 12-lead surface ECG of all patients were taken before the ECT, 15 min. after ECT and 24 hour after ECT.

Results: QRS duration, QT interval and corrected QT (QTc) interval were not changed significantly during the follow-up period. However, we found that, fQRS-T angle was significantly increased 15 minutes after ECT compared to baseline angle (p<0.001). We also detected that this increase in fQRS-T angle 15 minutes after ECT was significantly reduced 24 hours after ECT (p=0.031). Meanwhile, there was no significant difference between baseline and 24th hour fQRS-T angle (p=0.154).

Conclusions: In our study, a significant increase in fQRS-T angle was observed 15 min after ECT. However, the fQRS-T angle was found to return to normal after 24 hours. Our findings may indicate that ECT does not have a permanent side effect on the risk of cardiovascular events according to the fQRS-T angle.

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来源期刊
Inverse Problems
Inverse Problems 数学-物理:数学物理
CiteScore
4.40
自引率
14.30%
发文量
115
审稿时长
2.3 months
期刊介绍: An interdisciplinary journal combining mathematical and experimental papers on inverse problems with theoretical, numerical and practical approaches to their solution. As well as applied mathematicians, physical scientists and engineers, the readership includes those working in geophysics, radar, optics, biology, acoustics, communication theory, signal processing and imaging, among others. The emphasis is on publishing original contributions to methods of solving mathematical, physical and applied problems. To be publishable in this journal, papers must meet the highest standards of scientific quality, contain significant and original new science and should present substantial advancement in the field. Due to the broad scope of the journal, we require that authors provide sufficient introductory material to appeal to the wide readership and that articles which are not explicitly applied include a discussion of possible applications.
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