Abdulrahman Alfawzan, Saeed Alshahrani, Ahmad Alswaidan, Ala Alkharaan, Hayyaf S Aldossary, Awad M. Almuklass
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引用次数: 0
摘要
多发性硬化症(MS)是一种影响中枢神经系统的自身免疫性疾病,以神经元脱髓鞘和有限的再髓鞘为特征。人们越来越倾向于将过敏史与多发性硬化症联系起来。多发性硬化症和1型过敏都是由过度反应的免疫系统引起的。这两种疾病相似的环境和遗传因素进一步加强了这一点。这篇综述探讨了1型过敏性疾病史与MS风险之间的关系,以及研究地点对这种关系的影响。文献检索是通过沙特数字图书馆搜索引擎进行的,其中包括许多数据库,如PubMed和Web of Science;检索了有关多发性硬化症和1型过敏之间关系的文章。在这篇综述中,大多数研究显示1型过敏史和ms之间呈负相关或无相关,大多数文章得出的结论是这种关系没有统计学意义。一项研究表明,哮喘会增加多发性硬化症的风险。地理位置不影响MS和过敏的关联。
Is a History of Type 1 Allergic Diseases Associated with the Risk of Developing Multiple Sclerosis?
Multiple Sclerosis (MS) is an autoimmune disorder affecting the central nervous system, characterized by demyelination of the neurons with limited remyelination. There has been a rising trend toward associating a history of allergy with MS. Both MS and type 1 allergies are developed by a hyper-reactive immune system. This is further reinforced by the similar environmental and genetic factors of both diseases. This review examines the association between a history of type 1 allergic diseases and the risk of MS, as well as the influence of study location on the association. A literature search was conducted through the Saudi Digital Library search engine, which includes many databases, such as PubMed and Web of Science; articles addressing the relationship between MS and type 1 allergies were retrieved. In this review, most studies show an inverse or no association between type 1 allergy history and MS. Most articles concluded that the relationship is not statistically significant. One study stated that asthma increases MS risk. Geographical location does not influence MS and allergy association.