V. Bueva, E. V. Blynskaya, K. Alekseev, S. Tishkov, S. V. Minaev, M. S. Vykhristyuk
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Main approaches to evaluating the quality of chewable tablets and medicated chewing gums
Chewable tablets and medicated chewing gums are currently gaining importance in the pharmaceutical market due to their numerous advantages such as the ease of use, rapid onset of pharmacological effect, and high patients’ compliance, in particular, of dysphagia patients. The usage of chewable tablets and medicated chewing gums involves special methods for evaluating their textural, structural and mechanical characteristics, as well as individual methods for studying the drug release. The review provides an analysis of the main methods for studying structural, mechanical, and technological characteristics of chewable tablets and medicated chewing gums. In addition, the principles of operation and design of test devices, as well as pharmacopoeial methods for evaluating the drug release, are shown.