基于缩合的胺 C-H 键官能化方法。

IF 0.7 Q3 EDUCATION & EDUCATIONAL RESEARCH

Changing English-Studies in Culture and Education Pub Date : 2021-11-01 Epub Date: 2021-09-02 DOI:10.1055/a-1631-2140

Weijie Chen, Daniel Seidel

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引用次数: 0

摘要

本综述旨在全面概述以偶氮甲基酰化物为关键中间体的胺 C-H 键官能化缩合方法。这些转化通常是氧化还原中性的，与经典的命名反应（如 Strecker、Mannich、Friedel-Crafts、Pictet-Spengler 和 Kabachnik-Fields 反应）具有共同属性，同时包含氧化还原异构化步骤。这种方法为将简单的起始材料快速转化为复杂的胺提供了一个理想的平台。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Condensation-Based Methods for the C-H Bond Functionalization of Amines.

This review aims to provide a comprehensive overview of condensation-based methods for the C-H bond functionalization of amines that feature azomethine ylides as key intermediates. These transformations are typically redox-neutral and share common attributes with classic name reactions such as the Strecker, Mannich, Friedel-Crafts, Pictet-Spengler, and Kabachnik-Fields reaction, while incorporating a redox-isomerization step. This approach provides an ideal platform to rapidly transform simple starting materials into complex amines.

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来源期刊

Changing English-Studies in Culture and Education EDUCATION & EDUCATIONAL RESEARCH-

CiteScore

1.60

自引率

25.00%

发文量