新型硫代氨基脲衍生物及其Mn(II)、Ni(II)、Cu(II)和Zn(II)配合物:合成、表征和体外生物筛选

Q2 Chemistry

Current Chemistry Letters Pub Date : 2023-01-01 DOI:10.5267/j.ccl.2022.12.010

Bansuri Nandaniya, Siva Prasad Das, D. Jani

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引用次数: 1

摘要

本文合成了新的硫代氨基脲基席夫碱配体及其Mn(II)、Ni(II)、Cu(II)和Zn(II)配合物。对合成的化合物进行了表征，并对其抗菌活性进行了研究。元素分析、IR、1H-NMR和质谱分析对所有化合物进行了全面表征。筛选配体及其配合物对革兰氏阳性菌(枯草芽孢杆菌)和革兰氏阴性菌(大肠杆菌、肺炎克雷伯菌、铜绿假单胞菌)进行抑菌带法体外生物学研究。以硫代氨基脲为基础的配合物表现出比配体更好的活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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New thiosemicarbazone derivatives and their Mn(II), Ni(II), Cu(II) and Zn(II) complexes: Synthesis, characterization and in-vitro biological screening

In the present work, we synthesized new thiosemicarbazone based Schiff base ligands and their Mn(II), Ni(II), Cu(II) and Zn(II) complexes. The synthesized compounds were characterized and their antimicrobial activities were studied. Elemental analysis, IR, 1H-NMR and mass spectrometry were done to fully characterize all the compounds. The ligands and their complexes were screened for in-vitro biological study against Gram positive (Bacillus subtilis) and Gram negative (E. coli, Klebsiella pneumonia, Pseudomonas aeruginosa) bacteria for the Zone of Inhibition method. The thiosemicarbazone based complexes showed better activity than the ligands.

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来源期刊

Current Chemistry Letters Chemistry-Chemistry (all)

CiteScore

4.90

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： The "Current Chemistry Letters" is a peer-reviewed international journal which aims to publish all the current and outstanding research articles, reviews and letters in chemistry including analytical chemistry, green chemistry, inorganic chemistry, organic chemistry, physical chemistry, etc. This journal is dedicated to serve all academic and industrial researchers and scientists who are expert in all major advances in chemistry research. The journal aims to provide the most complete and reliable source of information on current developments in these fields. The emphasis will be on publishing quality articles rapidly and openly available to researchers worldwide. Please note readers are free to read, download, copy, distribute, print, search, or link to the full texts of articles published on this journal. Current Chemistry Letters is an open access journal, which provides instant access to the full text of research papers without any need for a subscription to the journal where the papers are published. Therefore, anyone has the opportunity to copy, use, redistribute, transmit/display the work publicly and to distribute derivative works, in any sort of digital form for any responsible purpose, subject to appropriate attribution of authorship. Authors who publish their articles may also maintain the copyright of their articles.