闭塞性细支气管炎:食用雌雄同体龙后组织肺炎

Rong-Hsin Yang, Sha Yao, Y. Chu
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引用次数: 0

摘要

闭塞性支气管炎组织肺炎(BOOP)是一种罕见的疾病,影响小气道,肺泡和小支气管壁。这种形式的肺损伤包括炎症和有组织的肺区域硬化。有几种已知的引起BOOP的原因,一些全身性疾病有BOOP作为相关的原发性肺病变。1994年年底以来,台湾曾公开报道年轻妇女中爆发了BOOP。这种疾病的源头可以追溯到食用了雌雄同体的蜥脚类动物。在这里,我们描述了一个28岁的妇女谁发展了一个快速肺毒性后,每天饮用新鲜的雌雄同体pursamae,为期两个月,所谓的减肥方案。Ga-67柠檬酸显像显示了她的眼睛、腮腺和肺部的炎症状况。开肺活检标本病理表现为BOOP的特征。这种毒性被认为与植物中含有的生物碱罂粟碱有关。雌雄同体S. androgynus的生物活性原理和BOOP的发病机制尚不清楚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bronchiolitis Obliterans Organizing Pneumonia Following Consumption of Sauropus androgynus
Bronchiolitis obliterans organizing pneumonia (BOOP) is a rare disorder affecting the small airways, alveoli and the walls of small bronchi. This form of lung injury involves inflammation and stiffening of lung areas with organized tissue. There are several known causes of BOOP, and several systemic disorders have BOOP as an associated primary pulmonary lesion. An outbreak of BOOP among young women has been publicly reported in Taiwan from late 1994 and onward. The source of the illness was traced to the consumption of Sauropus androgynus. Herein, we describe a case of a 28-year-old woman who developed a rapid pulmonary toxicity after drinking fresh S. androgynus purée daily for a period of two months, as an alleged regimen for weight reduction. Ga-67 citrate imaging portrayed the inflammatory status in her eyes, parotids and lungs. Pathological pattern of open-lung biopsy specimens was characteristic of BOOP. The toxicity is believed related to alkaloid papaverine contained in the plant. Bioactive principles of S. androgynus and pathogenetic mechanism underlying BOOP remain unidentified.
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