药物洗脱支架在高须动脉炎合并肾动脉狭窄中的作用

IF 0.2 Q4 PEDIATRICS
I. K. A. Utamayasa, Mia Puspitasari, Taufiq Hidayat, M. A. Rahman
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引用次数: 0

摘要

高松动脉炎(Takayasu arteritis, TA)被定义为累及主动脉及其主要分支的大动脉肉芽肿性炎症。高须动脉炎合并肾动脉狭窄(TARAS)是小儿肾血管性高血压的常见病因。TARAS治疗的主要目的是改善高血压和恢复肾功能。当一般药物治疗不能改善症状时,可以尝试肾脏血运重建术。药物洗脱支架(DES)的植入已被用作儿童肾脏血运重建术的替代策略。在此,我们报告一位10岁的爪哇女性双侧TARAS患者接受DES植入。她的临床表现为高血压危象和肾功能恶化。双侧肾动脉DES植入成功,无并发症。DES植入后患儿血压得到控制,两种降压药治疗,肾功能恢复。给予双重抗血小板治疗以减少支架血栓形成的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of drug-eluting stent on Takayasu arteritis with renal artery stenosis
Takayasu arteritis (TA) is defined as granulomatous inflammation of large arteries involving the aorta and its primary branches. Takayasu arteritis with renal artery stenosis (TARAS) is a common cause of pediatric renovascular hypertension. The main purposes of TARAS management are to improve high blood pressure and recover renal function. When general medication fails to improve symptoms, renal revascularization may be attempted.  Implantation of a drug-eluting stent (DES) has been used as an alternative strategy for pediatric renal revascularization. Here, we report on a 10-year-old, female, Javanese patient with bilateral TARAS who underwent DES implantation. Her clinical presentation was hypertensive crisis and worsened renal function. Bilateral renal artery DES implantation was performed successfully without complications. The child’s blood pressure was controlled using two anti-hypertensive medications after DES implantation and her renal function recovered. Dual anti-platelet therapy was given to minimize the risk of stent thrombosis.
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
58
审稿时长
24 weeks
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